pharmacology receptor agonists antagonists

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Author:
iishvo
ID:
235466
Filename:
pharmacology receptor agonists antagonists
Updated:
2013-09-17 21:31:18
Tags:
enzymes receptors agonists antagonists noradregenic cholinergic
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pharmacology notes
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  1. Noradregenic Transmission
    Beta and Alpha
  2. Cholinergic Transmission
    muscarinic and nicotinic
  3. Beta 1 Agonist
    Dobutamine
  4. Beta 1 Antagonist
    atenolol, metaprolol
  5. Beta 2 Agonist
    albuterol, terbutaline
  6. Beta 2 Antagonist
    butoxamine
  7. Alpha 1 Agonist
    phenylephrine,pseudoephrine
  8. Alpha 1 Antagonist
    prazosin,doxazosin
  9. B1/B2 antagonist
    propanolol
  10. Muscarinic Agonists
    AcH,pilocarpine,carbachol
  11. Muscarinic Antagonists
    atropine, scopolamine
  12. Nicotinic Agonists
    succinylcholine
  13. Nicotinic Antagonists
    atracurium, tubocuranine,vecuronium
  14. Nictonic Rectepors
    ligand gated and present in skeletal muscle
  15. 3 classes of receptors
    muscle, ganglionic, CNS
  16. Muscarinic receptors
    g-protein coupled and smooth muscle
  17. M1
    neuronal
  18. M2
    Cardiac
  19. M3
    smooth muscle
  20. M4/M5
    CNS
  21. Nicotinic agonists are also called
    depolarizing blockers
  22. Nicotinic antagonists are also called
    non-depolarizing blockers
  23. Nicotinic antagonist characteristics
    block AcH, no depolarization
  24. Muscarinic agonists characteristics
    mainly in glaucoma; used to constrict pupils and contraction of ciliary muscle
  25. Muscarinic antagonists
    inhibit secretions, increast heart rate (tachycardia), dilate pupils, GI motility inhibited, relax smooth muscle, and CNS excitatory effects (restlessness)
  26. B1 found in?
    heart
  27. B2 found in?
    smooth muscle
  28. B3 found in?
    skeletal muscle
  29. alpha 2 is found in?
    nerve terminal-feedback loop
  30. beta agonist characteristic
    cause relaxation (mainly B2)
  31. Beta antagonist characteristic
    decrease (chronotropic) and force (intropic) [mainly B1]
  32. Alpha agonist
    arteries/veins constricted which increase venous pressure/resistance and leads to increase systolic/dystolic pressure and heart rate
  33. Alpha antagonist
    cause vasodilation and decrease pressure

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