Histo slides 50-90

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  1. Image UploadWhat is this photo a condition of? How is this caused?
    • Image Upload§recessive single point mutation of gene coding for B-globin of hemoglobin (normal HbA)
    • §substitution of a single amino acid valine (hydrophobic) for glutamic acid (hydrophilic)§Abnormal hemoglobin (HbS) CLUMPS under low O2 tension
  2. Image UploadWhat is this photo? What other 2 complications can it lead to and how?
    • EM of a homozygous HbS Sickle cell, more rigid and has less O2.
    • 1. Stroke- can plug vessels
    • 2. Anemia- vessels fragile & break easily
  3. Image UploadLabel:
    • A. Neutrophil (segmented nucleus, neutral stain)
    • B. Platelets/ Thrombocytes
    • C & D. Sickle Red Blood Cell
  4. Image UploadWhat condition does this person have?
    Sickle Cell Anemia; note sickle red blood cell shape.
  5. Image UploadLabel
    • A: Howell-Jolly Bodies
    • B. DNA fragments
    • C. Normal Blast (immature RBC; still has it's nucleus)
  6. Name 1,2,3 conditions and label cells A,B, C
    • 1. Parasitic infection A. Parasite infecting RBC
    • 2. Parasitic infection B. Parasite infecting RBC
    • 3. Lead Poisoning C. Basophilic stippling
  7. Image Upload Label
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  8. Image UploadImage Upload
  9. Image UploadWhat is this?
    Neutrophil. Note segmented nucleus + neutral color stain.
  10. Image Upload
    Neutrophil. Segmented nucleus
  11. Image UploadWhat is cell 3? What is A & B?
    Neutrophil A. is 3 lobed (3 or 5 is usual) B. Barr Body seen in 3% females and NOT used for sex determination.
  12. Image UploadLAbel
    • A. Neutrophil
    • B. Specific Granules
    • C. Azurophilic Granules
  13. Image UploadWhat is this?
    2 Neutrophils surrounded by RBC and some platelets.
  14. Image UploadWhat is this?
    3 Neutrophils surrounded by rbv
  15. Image UploadLabel
    Image Upload
  16. Image UploadLabel
    Image UploadMovement of Neutrophil
  17. Image UploadWhat does this depict? Label
    Image Upload
  18. Image UploadWhat is this?
    There is a large focus of neutrophils. This is a smoker's lungs.
  19. Image UploadOverall, what  condition does this tissue sample depict and how can you tell?
    Inflammation. Many WBC numerous throughout.
  20. Image UploadWhat kind of cell and label.
    Image Upload
  21. Image UploadWhat is this?
    Eosoniphils with specific granules that Stain BRIGHT RED and are refractive with the light microscope
  22. Image UploadWhat is this?
    EOSINOPHILES §Center of each granule has a crystalloid body with TEM§CRYSTALLOID BODIES contain:-major basic protein (MBP)-eosinophil cationic protein (ECP)-eosinophil peroxidase (EPO)-   eosinophil - derived neurotoxin (EDN)
  23. Image UploadWhat kind of cell is this? How can you tell?
    Eosinophilic granules are clearly seen. Each granule has a disk-shaped electron-dense crystalline core that appears surrounded by a matrix enveloped by a unit membrane.
Card Set:
Histo slides 50-90
2013-09-20 00:32:51
Saba university histology blood

Histo slides 50-90
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