3220: Arthirtis

Card Set Information

Author:
jam110007
ID:
236796
Filename:
3220: Arthirtis
Updated:
2013-09-24 22:53:39
Tags:
arthritis 3220
Folders:

Description:
3220 exam 1 arthritis
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user jam110007 on FreezingBlue Flashcards. What would you like to do?


  1. systemic autoimmune rheumatic diseases are considered _____ disorders
    are considered chronic disorders
  2. examples of systemic autoimmune rheumatic diseases
    • - rheumatoid arthritis [RA]
    • - systemic lupus erythematosis [SLE]
  3. systemic autoimmune rheumatic diseases are characterized by?
    • - diffuse inflammatory vascular lesions [inflammation of blood vessels]
    • - degeneration of connective tissue
  4. incidence of rheumatoid arthritis
    1/100, slow onset
  5. ration of women to men that are affected with rheumatoid arthritis
    2-3 : 1  women : men
  6. peak onset age for rheumatoid arthritis is?
    30-50 yo
  7. risk factor for rheumatoid arthritis
    smoking
  8. what percentage of people have the rheumatoid factor [RF]
    80 %
  9. what is the rheumatoid factor
    it is an antibody to self antigens that are being identified as foreign in the body - IgG, IgM, with altered amino acids
  10. what percentage of healthy people have the rheumatoid factor [RF]
    1-5 percent
  11. pathology of synovial membrane
    • - growth of new blood vessels "panus" that extend from the synovium to articular cartilage 
    • - inflammatory cells in pannus destroys adjacent cartilage and bone which is irreversible
  12. bouchard's nodes
    • occurs in the hand of a person with RA, the joints swell to the side and pull slightly apart
    • - can be painful
  13. types of joint deformities in RA
    • - ulnar drift
    • - swan's neck
    • - nodes
    • - muscle wasting
    • - hip and leg deformities
  14. what is ulnar drift
    • - found in RA
    • fingers tend to bend toward the ulnar side of the wrist [bend away from thumb]
  15. what is sawn's neck
    • found in RA
    • - some joints will hyper-extend and bend in one direction and then another
  16. treatment of RA
    • - rest [physical and emotional]
    • - physical therapy [ROM] [more passive instead of weight bearing]
    • - assistive devices
    • - education
    • disease modifying agents
    • - antiinflammatory agents
  17. antiinflammatory agents for RA include [prescribed]
    • - NSAIDs
    • - corticosteroids 
    • - gold
    • - immunosuppresion
    • - minocycline [antibiotic]
  18. which prescribed antiinflammatory causes more problem in pts with RA
    corticosteriods
  19. antiinflammatory agents for RA [OTC]
    • - gamma linolenic acid 
    • - Capsaicin [zostrix]
  20. Capsaicin [Zostrix]
    • - OTC agent used for RA
    • - used to relieve pain
    • - decreases substance P which increases pain
  21. disease modifying antirheumatic agents [DMARD]
    - has antiproliferative effects which stop structural damage
  22. name a few disease modifying antirheumatic agents
    • - low-dose methotrexate
    • - leflunomide [arava]
    • - entanercept [enbrel]
    • - adalimumab [humira]
  23. facts about RA and taking etanercept [enbrel] and adalimumab [humira]
    • - binds to TNF, prevents receptor interaction 
    • - can use with methotrexate
    • - 2x weekly enbrel or 2x monthly with humira
  24. osteoarthritis
    • - also know as "degenerative joint disease" [DJD]
    • - 1/3 by age 60
    • - loss of articular cartilage
    • - NO inflammation in initial stages
    • - joint pain, stiffness that last less then 30 mins, instability, deformity
    • - secondary synovitis > mild
    • - weight bearing joints, ASYMMETRICAL, bas of the thumbs and fingers
  25. primary osteoarthritis due to
    - unknown etiology
  26. secondary osteoarthritis due to
    - due to injury, wear and tear, obesity
  27. treatment of OA
    • - weight loss
    • - acetaminophen for pain
    • - corticosteriod injections in joint [only for less then 3 years - may accelerate joint destruction]
    • - surgery [arthoscopic lavage, total joint replacement]
    • hyaluronate injections [hyalgan] - compund that's similar to the hyaluronic acid  in the body
    • synvisc [inject into the synovial bag to widen the joint a bit - last about 3 months]
    • high dose folat/b12
    • - glucosamine, chondrotin [OTC, helps widen the joint and fill with fluid again]

What would you like to do?

Home > Flashcards > Print Preview