Amino Acids/Biochemistry

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Author:
stefanyoli787
ID:
237588
Filename:
Amino Acids/Biochemistry
Updated:
2013-09-28 21:23:35
Tags:
Biochemistry Amino Acids
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Description:
Amino Acids Biochemistry
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  1. Amino Acids are the building block of
    proteins
  2. There are 20 commonly occurring amino acids.They have
    • the capacity to polymerize
    • varied structures
    • chemical functions in the amino acids chains
    • chirality
  3. All amino acids except for proline have both
    free α-amino and free α-carboxyl groups
  4. Amino acids are classified as
    • non-polar or hydrophobic
    • neutral but polar amino acids
    • acidic amino acids
    • basic amino acids
  5. Non polar amino acids. Include the amino acids with alkyl chain R groups
    • alanine
    • valine
    • leucine
    • isoleucine
    • proline (cyclic structure)
    • methionine (sulfur containing amino acid)
    • phenylalanine
    • tryptophan (aromatic)
  6. Polar uncharged amino acids
    • contain R groups that can make H bonds with water (except for glycine)
    • are more soluble in water than hydrophobic amino acids
    • tyrosine has the lowest solubility in water
    • proline is very soluble in water
  7. Good H-bond formation groups
    • amide group of asparagine and glutamine
    • hydroxyl group of tyrosine, threonine, and serine
    • sulfhydryl group of cystein
  8. Glycine
    has a single R group for H-bond formation
  9. Acidic amino acids
    • aspartic acid and Glutamic acid
    • contain a carboxyl group in their R side chain
    • they exist as COO- in neutral pH
    • proteins with negatively charged aa bind to metal ions
    • carboxyl groups can act as nucleophile in enzyme reactions
  10. Basic amino acids
    • histidine – imidazolium group
    • arginine – Guanidinium group
    • lysine – Protonated alkyl group

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