Connective Tissue Lecture (Last part) slides 121-165
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What kind of cell is this? Where can you find it? What 4 things does this cell have?
- Mast cell in muscle. Has:
- 1. SRS-A: slow responding s anaphylaxis (bronchospasm)
- 2. Heparin anti clot
- 3. Histamine (cause edema & anaphylaxis)
- 4. NEC: Neutrophil & Eosinophilic Chemoattractors
What is this a photo of?
Mast cells (large red, related to B cells) are releasing histamine (white) for allergic or immune reaction causing swelling (edema) or anaphylaxis.
Label. Where cells A differentiated from aka, what can make them?
- A: Adipose
- B: Sweat glands
- Mesenchymal AND fibroblasts can make more adipose cells.
- A: Adipose cells
- B: Nucleus pushed to the side of adipose cell
- C: blood vessel
What is the white cell? What are the arrows?
Adipose cells surrounded by EXTERNAL LAMINA
Label. How can you tell the difference?
- A: Mature fat cell
- B: Immature fat cell
- Difference: Immature lipids are smaller in size and have dark centrally located nucleus.
A: Fat cell (one droplet)B: Nucleus pushed to one sideC: Cytoplasm
- Right: Lipid Droplet,
- Top Left: EV (vesicles?)
- Far left : basal lamina aka external lamina
- Bottom Left: Smooth ER?
Brown fat. X 150 note large blood vessels(B). Brown adipose are central nucleus (A).
Label. Where could you find this?
Small blood vessel. Left nucleus – endothelial cell Right nucleus – pericyte. Note basal lamina of endothelial cell divides to surround the pericyte. CL, capillary lumen.
Bm, basal lamina; e, endothelial cell; p, pericyte. BM surrounds BOTH pericyte cell and wall of endothelial cells of large venules.
Compare the size of the lymphocyte (upper left corner) with mast cell in the middle of the TEM micrograph. X6000.
What is this a photo of? What is it a clone of?
- Arrows: Golgi
- Prominent component of:•loose connective tissue of GI tract•respiratory tract•salivary glands •lymph nodes•hemopoietic tissue.
What type of cell is this? How can you tell?
Plasma cell. Nucleus with cartwheel spokes like heterochromatin.
Label. What do presence of these cells indicate?
- A Fibroblasts nuclei
- B Plasma cells
- C Basilphils
- D Eosinophils
- Acute inflammatory reaction
What is this? Where is it commonly found?
Eosinophils are seen in normal connective tissue of the GI tractnNamed for the large, eosinophilic, granules in cytoplasmHave a role in allergic reactions.
What cell is this? What is it's main role?
Eosinophil. Bilobed. Parasitic infection.
Rough ER on left. Plasma nucleus on right. Entire cell is plasma cell. Makes gene for ONE SPECIFIC ANTIBODY PROTEIN ONLY!
What kind of cell is this? How can you tell?
Eosinophil. Bilobed nucleus. Crystaloid bodies. Specific granules. Fights parasitic infections.
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