ClinMedV:Toxicology(Bromethalin Rodenticide and Cholecalciferol Rodenticide)
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Bromethalin is an uncoupler of what in the CNS? OP
c.s. of bromethilin are dose dependent including:CPD
- cerebral edema
Symptoms of bromethalin are neurological at a high dose w/in 24 hrs=ETS
low dose bromethalin 1-5d=TDA
tx of bromethalin remembering that the efficacy of this is not as good once signs appear:DMGDP
- decontaminate GI tract if early
- mannitol and glucocorticoids is cerebral edema
- diazepam and phenobarbitol if seizures
How long can it take to improve from bromethalin?
What is cholecalciferol and where can it be found?
- vitamin D3
- found in supplements and older rodenticides
What does cholecalciferol cause?
calcium reabsorption from the bones and intestines to the blood
What does cholecalciferol taking calcium from bones lead to?
hypercalcemia and calcification of tissues
What does cholecalciferol ultimately damage/cause?KSCN
- the kidneys
- soft tissue
With cholecalciferol how does death occur?HC
With cholecalciferol when do c.s. arise?
c.s./symptoms of cholecalciferol:AVMCHVSPC
- muscle weakness
- v fib
- calcium deposits if long term exposure
- activated charcoal
- electrolyte balace
Electrolyte balance is brought on by which IV fluids to decrease calcium reabsorption?fcp
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