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fascia
suspends the organs within their cavities and wraps them in layers of connective tissue
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meninges
visceral fascia for brain
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pericardium
connective tissue in heart
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pleurum
lung connective tissue
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peritoneum
connective tissue in abdomen
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reticular fibers
mesh of connective tissue
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areolar
found beneath the dermis around blood vessels nerves and joints (loose)
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fibroblast
make fibers of connective tissue
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tendons
dense connective tissue that attach skeletal muscle to bone
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ligaments
dense connective tissue connect one bone to another (has elastin so it is flexible)
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microphages
large white blood cells that eliminate cellular debris and particulate antigens, including bacteria, through phagocytes
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cartilage
dense array of fibers in a jellylike ground substance (dense connective tissue)
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dense connective tissues
- slow to heal
- no blood supply in connective tissues
- infections hard to treat
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strain
stretched or injured TENDON
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Sprain
Ligaments are damaged
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adipose tissue
form of loose connective tissue that stores fat, which acts as a source of energy and acts as a cushion
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bone
flexible protein matrix consisting of collagen fibers and other proteins on which calcium phosphate, a mineral crystal, is deposited
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bone marrow
- create blood
- inside of bone
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function of blood
- transport oxygen and nutrients
- carry away waste and co2
- stabilize pH
- carried white blood cells to infection
- equalize temperature
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plasma
- liquid in blood
- 91%water
- 9% salts (ions)
- proteins
- dissolved minerals
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cells of blood
- red blood cells
- white blood cells (5 different types ,All play a role in immune response)
- platelet
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white blood cells
- 5 different types (neutrophils, lynphocytes, monocytes, eosinophils, basophils)
- made in red bone marrow
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erythrocytes
- red blood cells
- most numerous cells in blood
- deliver oxygen and carbon dioxide
- hemoglobin
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3 types of plasma proteins
- albumin
- globulin
- fibrinogen
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albumin
- most abundant plasma protein
- important for plasma's osmotic pressure as well as transportation
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hemoglobin
iron containing oxygen-transport protein in red blood cells
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hemoglobin A (adult)
- 4 proteins that function as one
- 2 alpha proteins
- 2 beta proteins
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hemoglobin S (2alpha, 2sickle betas) sickle cell disease
- variant form of hemoglobin found in people with sickle cell disease
- variation of beta chain gene, causing a change in the properties of hemoglobin which results in sickling of red blood cell
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Globulin
plasma protein important in transportation
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fibrinogen
plasma protein important for the formation of blood clots
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leukocytes
- white blood cells
- derived from stem cells in bone marrow
- remove dead or worn-out cells and protect us against invading microbes and foreign agents
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Blood typing (ABO)
- neither - o blood type
- ao or aa - a blood
- bo or bb - b blood
- ab - ab blood
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Malaria
- falciparum malaria
- parasite in mosquitos
- develop in liver and go in blood cells
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leukemia
- cancer of white blood cells or cells that develop into white blood cells
- inadequate numbers of red blood cells
- increased risk of infection
- increase risk of bleeding
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Lymphomas
- cancer of Lymphocytes (particular white blood cells)
- -out of lymphatic to blood, spleen, organs
- -hodgkins and non-hodgkins
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systemic lupus erythematosus
- autoimmune
- attack connective tissue
- flares and remissions
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rheumatoid arthritis
- autoimmune,
- attacking joints
- stiffness, fever, muscle and joint aches, loss of appetite, and fatigue
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scurvy
- vitamin C deficiency
- defective collagen
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ehlers-danlos syndrome (EDS)
inherited disorders that weaken connective tissues
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Marfan syndrome
fibrillin, protein in one of the fibers of the extracellular matrix, is mutated
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Fibrosis
excessive deposition of extracellular matrix protein
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healing phases
- inflammatory phase
- proliferative phase
- remodeling phase
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