STD

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Author:
alvo2234
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239160
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STD
Updated:
2013-10-06 23:43:19
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Exam II
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Dr Mo AOC
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  1. what is the MOA of metronidazole
    • inhibits DNA synthesis
    • causes DNA breakage
    • inhibit respiration in anaerobic organisms
  2. what is the MOA of Acyclovir
    • inhibits viral DNA chain elongation
    • inactivation of viral DNA polymerase
  3. what is the MOA of foscovir
    binds to pyrophosphate sites on viral DNA polymerase and inhibits DNA synthesis
  4. what is the causative agent of genital warts
    HPV
  5. what is the causative agent of genital herpes
    • HSV-1
    • HSV-2
  6. what is the causative agent of trichomoniasis
    trichomonas vaginalis
  7. what is the causative agent of chancroid
    haemophilus ducreyi
  8. what is the causative agent of lymphogranuloma venereum
    chlamydia trachomatis
  9. what is the causative agent of granuloma inguinale
    klebsiella granulomatis
  10. what is the distinguishing features of bacterial vaginosis
    • clue cells (squamous cells loaded with rods)
    • whiff test (10% KOH + vag secretion)
    • light and homogenous secretion
    • dysuria, pruritus, tenderness, dyspareunia
  11. what is the distinguishing features of trichomoniasis
    • purulent, greenish-yellow vag disharge
    • strawberry-like lesions
  12. what are the AE of Foscarnet
    • nephrotox
    • anemia
    • electrolyte imbalance
    • -decrease in Ca2+, K+, Mg2+, PO4-
    • -can have increase or decrease in PO4-
  13. agents used to treat genital warts
    • podophyllin
    • trichloracetic acid
    • podofilox
    • aldara
    • cryotherapy (liquid nitrogen)
    • atovirsen
    • laser surgery
    • accusite
    • intralesional (INF-alpha)-2b or 2a
    • Gardasil
    • Cervarix
  14. list agents used to treat intestinal amebiases
    • erythromycin (PO)
    • aminoglycosides
    • tetracyclines
  15. can agents used in intestinal amebiasis be used to treat extra-intestinal amebiasis
    NO
  16. agents used to treat extra-intestinal amebiasis
    • flagyl
    • tinidazole
    • emetine
    • chloroquine
    • *can also be used for intestinal
  17. agents used to treat giardiasis
    • flagyl
    • tinidazole
    • quinicrine
    • furoxone
  18. what is the route of administration of acyclovir
    PO, topical, IV
  19. how does food effect the oral absorption of acyclovir
    it does not effect it
  20. what is the f factor for acyclovir
    15-30%
  21. what is the t1/2 of acyclovir
    2.5 hours
  22. what is the PPB of acyclovir
    9-33% (very low)
  23. how is acyclovir excreted
    • renally (60-92%)
    • feces
    • pulmonary system as CO2 (expiration)
  24. tinidazole
    • tindamax
    • trichamonas
  25. clotrimazole
    • lotrimin
    • trichomonas
  26. clindamycin
    cleocin (trichomonas)
  27. viramidine
    taribavarin (Hep C)
  28. Ribavarin
    Rebtol (Hep C)
  29. Baraclude
    entecavir (hep b)
  30. famvir
    famciclovir (hep b and herpes)
  31. emtricitabine
    emtriva (hep b)
  32. telbuvidine
    tyzeka (hep b)
  33. gardisil
    HPV vaccine (warts)
  34. Cevarix
    HPV vaccine (warts)
  35. trichloracetic acid
    tri-chlor (warts)
  36. podofilox
    (condylox) warts
  37. aldara
    imiquimod (warts)
  38. valacyclovir
    Valtrex (herpes)
  39. ganciclovir
    cytovene (herpes)
  40. valganciclovir
    valcyte (herpes)
  41. pensiclovir
    Denavir (herpes)
  42. rebetol
    ribavirin (herpes, hep c)
  43. phosphonoformic acid
    foscarnet
  44. foscovir
    foscarnet
  45. foscarnet
    phosphonoformic acid, foscovir
  46. denavir
    pensiclovir
  47. famvir
    famciclovir
  48. valcyte
    valganciclovir
  49. cytovene
    ganciclovir
  50. valtrex
    valacyclovir
  51. imiquimod
    aldara
  52. condylox
    podofilox
  53. tri-chlor
    trichloracetic acid
  54. tyzeka
    telbuvidine
  55. emtriva
    emtricitabine
  56. famcilovir
    famvir
  57. entecavir
    baraclude
  58. taribavarin
    viramidine
  59. lotrimin
    clotrimazole
  60. tindamax
    tinidazole

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