kaplan test review

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kaplan test review
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2010-06-19 18:30:49
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  1. probenecid class
    and SE
    uricosuric

    • kidney stone
    • GI upset
    • rash
  2. geodon generic
    ziprasidone
  3. mirapex generic
    and class
    pramipexole

    Anti-Parkinson's Agent, Dopamine Agonist
  4. bromocriptine class
    SE
    Anti-Parkinson's Agent, Dopamine Agonist; Ergot Derivative

    cardiac
  5. which SSRI can be dosed qweek?
    fluvoxetine
  6. max dose of nortriptyline
    150mg/d
  7. mirtazapine dose

    brand
    class
    • Remeron
    • Antidepressant, Alpha-2 Antagonist

    15 mg nightly
  8. nuva ring frequency
    q month
  9. ortho- evra frequency
    patch q week x 3 weeks / month
  10. seasonale
    84 active pills, then 7 inactive pills

    menses q3mo
  11. Seasonique
    • regular OC
    • 21pills then 7
    • or 28 pills
  12. hydroxychloroquine SE
    eye problems
  13. PPD should be done before?
    Humira (Adalimumab) Antirheumatic, Disease Modifying; TNF blocker

    not Enbrel (Etanercept) TNF blocker
  14. Natalizumab
    Tysabri®

    • Gastrointestinal Agent,
    • for MS or Crohn's

    Prescribing program: TOUCH

    IV q4weeks
  15. Natalizumab
    combo/mono?
    monotherapy
  16. what drug can be used for prophylaxis?
    in slightly elevated uric acid level
    in moderately elevated uric acid
    colchicine

    Allopurinol
  17. lithium reference level
    0.6-1.5mEq/L
  18. valproic acid level
    50-100mcg/mL
  19. antidepressants can also be used for?
    migraine prophylaxis
  20. Daypro
    oxaprozin

    • NSAID
    • propionic acid
  21. Mobic
    maloxicam

    more COX-2 selective, but still prossess potential to cause GI upset
  22. Haloperidol requires monitoring of?
    baseline ECG

    periodic CBC
  23. which antidepressant an increase blood pressure
    • venlafaxine
    • duloxetine (cymbalta)
    • desvenlafaxine (Pristiq)
  24. 1st line for gout
    NSAID indomethacin
  25. mirtazapine SE
    • somnolence
    • dosed at bedtime
  26. what should be given in combo with infliximab?
    MTX

    • brand: Remicade
    • class: Antirheumatic, Disease Modifying; TNF alpha blocker
  27. triptan that are no PO (4)``
    • Imitrex injection
    • Imitrex nasal spray
    • Zomig ODT (zolmitriptan)
    • Maxalt MLT (rizatriptan)
  28. lithium significantly interacts with?
    • ACEI
    • diuretics
  29. valproic acid is CI in?
    hepatic dysfunction
  30. valproic acid work by
    • inactivates Na channels
    • increase GABA
  31. hydroxychloroquine for

    SE
    (SLE) and rheumatoid arthritis

    eye damage
  32. oxybutynin

    brand?
    class?
    SE
    Ditropan; Ditropan XL; Oxytrol patch

    Antispasmodic Agent, Urinary

    anticholinergic
  33. estrogen deficiency
    • hot flashes
    • spotting
    • breakthrough bleeding
    • libido
    • dyspareunia (painful intercourse)
  34. breast tenderness
    cyclic weight gain
    edema
    bloating
    HTN
    melasma (tan face)
    nausea
    migraine
    estrogen excess
  35. libido
    depression
    fatigue
    weight gain
    acne
    hypomenorrhea
    vaginal candidiasis
    progestin excess
  36. heavy menses
    weight loss
    delayed menses
    spotting
    breakthrough bleeding
    progestin deficiency
  37. topiramate metabolism
    • inhibit 2C19
    • induces 3A4
  38. grapefruit juice and 3A4
    inhibit
  39. detrol generic
    tolteradine
  40. vesicare generic
    solifenacin

    Treatment of overactive bladder
  41. tofranil generic
    class
    imipramine

    tricyclic
  42. Enablex generic

    class
    darifenacin

    for bladder overactivity (anticholinergic)
  43. what drugs interact with aged cheese?
    (tyramine)

    • isoniazid
    • linezolid
    • rasagiline Azilect (parkinson's; MAO-B)
  44. Selegiline should not be used with what class of meds
    SSRI
  45. Buspar

    generic
    MOA
    indication
    Buspirone

    • affect
    • 5HT- 1A&2
    • D2

    for generalized anxiety disorder
  46. hypertrichosis is
    excessive hair growth
  47. anthralin
    Keratolytic Agent

    for psoriasis
  48. what does TNM stand for?
    • T: severity of the primary tumor
    • N: severity of lymph node involvement
    • M: severity of distant metastases
  49. neoadjuvant chemo and adjuvant chemo
    prior to surgery

    post surgery

    both increase survival
  50. cytarabine
    MOA
    inhibit DNA polymerase
  51. doxorubicin MOA
    anthracycline

    intercalating agent; interupt DNA syn
  52. cytarabine SE
    • neurotox
    • conjunctivitis
  53. Avastin
    bevacizumab

    target VEGF overexpression
  54. Gleevec
    imatinib

    • target bcr-abl fusion gene
    • Philadelphia (+)

    1st line in CML
  55. Tarceva
    erlotinib

    target DGFR overexpression
  56. Rituxan
    • rituximab
    • target CD20 antigen
    • add to CHOP or CVP in non-Hodgkin's lymphoma
  57. Aprepitant is used for

    brand?
    Emend

    delayed N/V caused by drugs (cisplatin, doxorubicin, cyclophosphamide, irenotecan, carmustine)
  58. 5FU SE
    hand and foot syndrome
  59. platinum and nitrogen chemos
    SE
    ototox
  60. caduet
    atorvastatin + amlodipine
  61. Advicor
    lovastatin + niacin
  62. digoxin tox
    • anorexia
    • arrhythmias
    • visual disturbances
    • and more?
  63. Bidil
    hydralazine and isosorbide dinitrate
  64. Inspra
    eplerenone
  65. bactrim and warfarin interaction
    increase INR
  66. reference that contain foreign drug info
    Martindale
  67. Ketek
    • telithromycin
    • macrolide
  68. how to take sulfasalazine?
    with food
  69. sulfasalazine SE
    • change body fluids to orange
    • photosensitivity
  70. DOC for C. diff
    metronidazole
  71. what resource have info in lay language?
    USP-DI volume II
  72. Cytotec
    misoprostol
  73. Dipentum
    Olsalazine

    • Maintenance of remission of ulcerative colitis in patients intolerant to
    • sulfasalazine
  74. cost info resource
    Red book
  75. SE of niacin
    • hyperglycemia
    • hperuricemia
    • flushing
  76. Combigan
    timolol + brimonidine (alpha 2 agonist)

    eye drop
  77. dorzolemide
    carbonic hydrase inhibitor
  78. wha'ts special with nitroprusside preparation?
    protect from light
  79. what are the Commission E monographs for?
    info on herbal products
  80. Clotrimazole availability
    • troche,
    • cream, solution, tablet
  81. amiodarone monitoring parameters
    LFT q 6mo

    chest x-ray q 12 mo

    thyroid funtion q 6 mo
  82. separate eyedrops by
    10 min
  83. Trissels
    • IV drug compatibility
    • stability info on drugs in comounded formulations
  84. MTX monitoring
    • CBC
    • LFT

    no ECG
  85. which PPI can be given thru NG tube?
    • nexium (open capsule)
    • prevacid (open capsule)
    • prilosec suspension (omeprazole)
  86. when should PPIs be taken?
    15-30mins before breakfast
  87. misoprostol should be taken....
    with meal
  88. tyramine foods can't be taken with?
    MAOIs
  89. amoxicillin available forms
    • suspension
    • capsule

    not IV. give ampicillin
  90. pregnancy safe antihypertensives
    • methyldopa
    • CCB
    • labetalol
  91. Sporanox
    itraconazole
  92. Aciphex
    rabeprazole
  93. how does amiodarone cause hypothyroidism
    it contains iodine
  94. what arrhythmias does amiodarone treat?
    atrial and ventricular
  95. Infliximab
    Remicade
  96. Zyflo
    • zileuton
    • 5-lipoxygenase inhibitor
  97. Tilade
    nedocromil

    mass cell stabilizer
  98. fish oil helps with what levels
    TG
  99. MOA of bupropion
    inhibit dopamine reuptake
  100. venlafaxine MOA
    inhibit serotonin, NE, and DA
  101. Anexate
    flumazenil
  102. opioid antidote
    • naloxone
    • nalmefene
    • naltrexone
  103. antidote for ethanol
    Antizol (fomepizole)
  104. antidote for cisplatin
    amifostine
  105. antidote of MTX
    leucovorin
  106. Cytomel
    • liothyronine
    • T3
  107. levothyroxine
    T4
  108. medroxyprogesterone
    progestin

    • SE:
    • weight gain
    • osteoporosis
    • PE
  109. how long does it take treansdermal fentanyl to reach plateau?
    24h
  110. how are morphine and codeine renally adjusted

    why?
    • 75% when CrCl 10-50
    • 50% when CrCl <10

    morphine's metaboliste, morphine-6-glucuronide, toxic in renal insufficiency
  111. Does oxycodone need dose adjustment?
    hepatically yes
  112. naproxen max dose
    1250mg/d
  113. IBU max dose
    3200mg/d
  114. SE of ferrous sulfate
    • constipation
    • dark stool
    • urine discoloration
  115. what is choleacalciferol
    vitamin D
  116. pyridoxine
    vit B6
  117. for isoniazid, cycloserine, hydrazine overdose
    pyridoxine
  118. ascorbic acid
    • tx and prevent scurvy
    • acidify urine
  119. treat iron deficiency anemia for how long?
    6 mo
  120. MOA of epoetin-alpha
    • induce erythropoisis
    • release reticulocytes (immature RBC)
  121. chronic isoniazid should be supplemented with?
    pyridoxine (Vit B6)
  122. organization responsible for controlling and regulating controlled substances
    Drug enforcement administration
  123. organization for approve medication for market
    FDA
  124. national provider indicators
    assign national provider number to all healthcare professionals
  125. which BPH meds interacts with warfarin? and which one doesn't?
    finesteride and dutasteride

    Saw palmetto
  126. Robitussin AC
    • guaifenesin
    • codeine
  127. Robitussin DM
    • dextromethrophan - for cough
    • guaifenesin- for mucus
  128. Robitussin CF
    • guaifenesin
    • dextromethorphan
    • phenylephrine - for cough
  129. Robitussin DAC
    • guafenesin
    • pseudoephedrine
    • codeine
  130. Robitussin PE
    • guaifenesin
    • pseudoephedrine (cough)
  131. rule of 1800
    • used to determine the insulin sensitivity factor
    • not withint the insulin pump settings
  132. doses of vitamin E >400 IU are known to ...
    increase cardiovascular events
  133. Merck Index
    precise, comprehensive info on chemicals, drugs, and biologicals
  134. Merck Manual
    diseases
  135. Remington
    pharmacy encylopedia for pharmacology, theoretical science, sterilization, practical pharmacy practice
  136. USP-NF II
    official monographs for drug structure, solubilities, assay and therapeutic category.
  137. Boniva once daily dosing
    2.5mg/d
  138. 1 grain = ? mg
    ~65mg
  139. convert simvastatin dose to lipitor dose
    2:1
  140. Rosuvastatin : lipitor
    1:2
  141. pravastatin to lipitor
    4:1
  142. weak acids form what salts
    sodium, calcium, potassium, or other cationic
  143. weak bases form what kind of salts
    hydrochloride or other anionic salts
  144. how does temperature affects rate constant
    increase 10 degree celcius, doubles the rate constant

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