Acute and chronic rhinitis

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Anonymous
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240245
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Acute and chronic rhinitis
Updated:
2013-10-12 19:32:06
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Dr Dupre
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Description:
PT IV Exam II
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  1. classes used to treat allergic rhinitis
    • 1st generation antihistamines
    • 2nd generation antihistamines
    • inhibitors of mast cell degranulation
    • corticosteroids
  2. mast cell degranulation inhibitors are derivatives of what
    benzopyrone
  3. antazoline
    vasocon A
  4. is vascon acidic or basic
    basic
  5. what ring structure is antazoline characterized by
    imidazole ring
  6. what type of metabolism can be expected from antazoline in the body
    aromatic hydroxylation and conjugation
  7. what is the chemical structure name for benadryl
    ethanolamine
  8. clemastine
    tavist
  9. how many chiral centers and diasteromers does clemastine have
    2 chiral centers and 4 diasteromers
  10. chlorpheniramine
    chlortrimeton
  11. name some characteristics of chlorpheniramine
    longer half life than most 1st gen antihistamines

    fewer central effects than ethanolamine and ethylenediamenes
  12. what is the decreased sedation of the 2nd generation antihistamines due to
    improved H1 selectivity and amphoteric structures
  13. which class is loratadine related to
    TCAs
  14. how is loratadine metabolized
    oxidation of ethyl carbamate to des-loratadine (not a direct hydrolysis)
  15. zyrtec is the metabolite of what
    hydroxyzine
  16. which classes is cetirizine related to
    • ethanolamine
    • ethylenediamine
  17. fexofenadine
    allegra
  18. cetirizine has what functional group
    piperazine
  19. allegra has what functional group
    piperidine
  20. fexofenadine is the metabolite of what
    carboxylic acid metabolite of terfenadine
  21. mometasone furoate
    nasonex
  22. ciclesonide
    omnaris
  23. how are corticosteroid anti-inflm compounds excreted from the body
    unchanged (or hydrolyzed) in the feces
  24. atrovent
    ipratropium bromide
  25. atrovent is similar to what agent
    atropine
  26. what is atrovent classified as
    an amino alcohol ester
  27. how is ipratropium metabolized
    by hydrolysis then excreted
  28. cromolyn sodium
    nasalcrom
  29. what is cromolyn classified as
    bischromone (benzopyrone)
  30. how long will it take for the max response of cromolyn
    2 - 4 weeks
  31. what is the drug of choice for rhinorrhea in pregnancy
    cromolyn
  32. how is cromolyn excreted
    unchanged in bile and urine

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