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What is Ferritin?
Where is it found?
- Protein inside of body cells that store iron
- Best estimation of body iron stores.
Commonly found in: Bone Marrow, Liver and Spleen
What medications are commonly responsible for macrocytosis without anemia?
- carbamezepine (Tegretol)
- Zidovudine (AZT)
- Valproic Acid (Depakote)
- Phenytoin (Dilantin)
Antipsychotics/SZ, Protease Inhibitors
Causes of microcytic anemias:
- Thalessemia - Normal RDW
- Fe Deficient - hypochromic
Normal Lab Values
RBCs, H&H, MCV, MCH/MCHC, RDW, Retics
- RBC: 4.2 - 5.4
- H&H: Ratio 1:3
- MCV: Mean Corpuscular Volume (Size)
- < 80 = Microcytic
- 80-96 = Normal
- > 96 = Macrocytic
- MCHC = Mean Corp. HgB, concentration
- 31-37 = Noromochoromic
- < 31 = hypochromic
RDW = Distribution. No > 15%
Reticulocytes = 1-2 %
At what age should a female receive their first pap test?
Age 21 or 3 years post coitus, whatever is first
Macrocytic Anemias include
- vitamin B12 (cyanocobalamin) or folic acid
- hypersegmented neutrophils