CAD and Antianginals

Card Set Information

Author:
jaime.davenport
ID:
240341
Filename:
CAD and Antianginals
Updated:
2013-10-13 13:37:24
Tags:
CAD anti anginals
Folders:

Description:
Pharm midterm fall 2013
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user jaime.davenport on FreezingBlue Flashcards. What would you like to do?


  1. Two main causes of angina
    • CAD
    • Coronary vasospasm
  2. Patients with history of angina should have _____ and know how to use it.
    Nitroglycerin sublingual

    If after first dose of no relief call EMS
  3. Patients with symptoms suggestive of CAD should be_______?
    referred to a cardiologist.
  4. Three major classes of anti angina drugs
    • Nitrates -long and short acting
    • BB
    • CCB
  5. MOA of nitrates
    relax vascular smooth muscle. They cause dilation of the peripheral arteries and veins as well as coronary arteries.  Reduction in preload and increased blood flow and oxygen supply to the myocardium.
  6. Nitrates are one of the first medications used for angina.  They are used to .....
    Stop an acute attack, prevent attacks, and for chronic treatment.
  7. SL nitro and acute attack
    • 0.3-0.4 SL at 3-5 minute intervals for 3 doses.
    • IF UNIMPROVED OR WORSE AFTER 5 MINUTES, CALL EMS. (IT SHOULD BE EFFECTIVE IN 1-2 MINUTES)
  8. How soon for thrombolytic therapy in MI
    1-3 hours of onset
  9. Long acting nitrates
    Isosoride, nitro patch
    maintain vasodilation continuously decreasing the workload of the heart and maintaining blood flow to the heart.
  10. Isosorbide
    • Start Low and Go Slow
    • Take on empty stomach
    • Short half life may have to take multiple doses per day.
  11. Nitrate tolerance

    Prevention
    • Tolerance can develop in as few as 7-10 days of ongoing treatment.
    •  
    • To prevent this need 10-12 hour nitrate-free intervals every day.
  12. Most common adverse effect of nitrates
    headache
  13. Teach patients to avoid use of other vasodilators while taking nitrates because it can cause severe _____?
    hypotension
  14. While pt taking nitrates have them
    keep diary of prn use
  15. Labs with nitrates
    cardiac enzymes and electrolytes at least every three months.
  16. Most common interaction with nitrates
    • ETOH
    • Can cause severe hypotension and cardiovascular collapse
  17. Geriatrics and nitrates
    • are at greater risk for syncope with nitrates
    • have patient sit or lie down before administering drug.
    • usually need lower dose
  18. Nitrate pregnancy category
    c
  19. Ranolazine (Ranexa)
    • MOA unknown
    • minimal effects on HR and BP
    • improves exercise duration and angina symptoms when added to patient therapy already on antianginals
  20. Notify healthcare provider if taking nitrates and have these symptoms
    • blurred vision
    • persistent headache
    • dry mouth

What would you like to do?

Home > Flashcards > Print Preview