Which layer of the heart is responsible for the pumping action of the heart?
The left ventricle is responsible for what?
What is the system called where the blood travels through the entire body?
Which circulatory system feeds heart?
What is the func of the AV node?
Slows the electrical impulse, check module for exact wording
What is atherosclerosis?
Disease involving the accumulation of lipids in the arteries causing narrowing
Narrowing of blood vessels (not sure I heard this right)
What are the different types of angina?
Pectoris, unstable, atypical, define each
Symptoms of angina?
Chest pain, shortness of breath
Most dangerous AV block?
3rd or complete
Least threatening AV block?
Basic principle behind Spect MPI?
Perfusion images are different between rest and stress
Is Lexiscan capable of producing bronchoconstriction?
% of pts exp 1st AV block with Lexi?
Has Lexiscan been tested in pts taking other heart meds?
Pts were on those meds but those meds werent evaluated
Renal: How was it measured?
What is the GFR range of pts studied?
15-59 (stage 3 and 4)
Which adeno receptors most associated with bronchoconstriction?
A2B and A3
Study: how many pts in asthma/copd trial?
Incidence of resp AEs?
Higher with Lexi, as expected because Lexi causes dyspnea
Not been accessed
Hepatically impaired patients?
No adjustment needed for .
What foods have caffeine?
What class is caffeine in?
What are some of the most common AEs to Lexiscan?
Dyspnea, HA, flushing
How is Lexi packaged? How many mls?
Single dose, prefilled 5ml syring
In the Adenoscan pi, contraindicated for what?
Adeno : what % of pts heart block may occur in?
What % of AEs occur later?
10.6% for several hours
Recommended dose of Adenoscan?
140mcg/kg/min for 6min
Lexi high, med, low affinity for A2a?
A1 affinity of Lexi vs. Adeno?
Lower by 10x
Lexi has? Affinity for A2B and A3?
Weak in any
Peak velocity, increase 2 fold in ? minutes
Return to baseline?
Aggrenox, dipyridamole, how long must they abstain?
Physician office reimbursement?
Lexi Infusion time?
Approx. 10 sec
How much reg in a syringe?
If pts with caffeine?
Reduction in the efficacy of detecting ischemic defects reversible
How many billable units?
How do you measure asthmatics?
FEV, forced expiratory volume
Goals of txing established?
Ease symptoms, reduce the risk of MI
In PI, should you have appropriate resuscitative measures available?
When office councils pt with copd/asthma. Can they have resp therapy before?
What does pt info say about pts w/ COPD/Asthma?
Patients with COPD or asthma should be informed to discuss their respiratory history and administration of pre and post-study bronchodilator therapy with their clinician before scheduling an MPI study with Lexiscan.
How did Lexi compare to adeno efficacy in the package insert ?