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What are the EC proteins?
-consists of what?
- made of what?
- a linear array of building blocks (Fn-modules)
- made of a sequence of about 30 independent FN-modules, which combine to make 5-6 larger functional domains
In fibronectin, each of the two polypeptide chains that make up a fibronectin molecule contain what?
- binding sites for components of hte ECM that help stabilize the structure; enhanced by mechanical forces that pull on the fibrous proteins--> unfold--> reveal binding sites
- binding sites for receptors on the cell surface that help stabilize attachment to the cell