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urethritis, discharge, IgA protease, attachment, endocytosis, multiplication, macrophages, TNFa, inflammation
dyspnea, smoking, ROS, IL8 TNFa, neutrophils, protease elastase, loss of alveoli, dDLCO, hyperinflation type ii resp failure, bullous
productive cough, environmental irritants, goblet metaplasia, CD8, neutrophils, macrophages, IL8, loss of ciliated cells, mucus hypersecretion and plugging, reduced lumen, infections