Tech- Hematologic Emergencies (Part 3)

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  1. Is IMHA usually seen with regenerative or non-regenerative anemia?
    regenerative b/c commonly seen w/ high reticulocyte counts
  2. What are spherocytes?
    small RBC lack central pallor
  3. When are spherocytes seen?IAB
    • IMHA
    • after blood transfusions
    • burn injuries
  4. Basophillic stippling is seen in what species as a response to anemia?
    • ruminants
    • cats
  5. When do you commonly see inc/ high numbers of howell jolly bodies? Why?
    • after spenectomy/spenic disorders
    • phagocytic cells of spleen would normally remove cells containing nuclear remnants
  6. A heinz body is a round ball of denatured Hgb that attaches to the cell wall. When is it seen?LDI
    • LSA
    • DM
    • inc T4
  7. How do you perform a platelet estimate?
    count 10 fields, avg x 15000
  8. In general, what is the average lifespan of most RBC's?
  9. Heinz bodies are best seen with what type of stain?
  10. What type of anemia is associated with howell jolly bodies?
    regenerative anemias
  11. Basophilic stippling can be seen in dogs that suffer from what condition?
    lead posioning
  12. What is another name for nucleated RBC?
  13. How many general clotting factors are there?
  14. What are two main phases of hemostasis?
    • primary/mechanical
    • secondary/chemical
  15. Which phase of hemostasis forms an unstable fibrin clot?
  16. Within the primary phase of hemostasis, what is the charged surface that attracts platelets?
    subendothelium of the vessel
  17. Which phase of hemostasis involves the coagulation cascade?
  18. What is the coagulation cascade?
    the process of coagulation factors undergoing chemical reactions and forming an extrinsic or intrinsic pathway
  19. What is the end result of the coagulation cascade?
    the formation of fibrin strands that forms the clot
  20. What are your 2 pathways for the activation of the coagulation cascade?
    • intrinsic
    • extrinsic
  21. Which pathway is surface activated, only using components of the blood?
  22. Which pathway requires a tissue factor for activation?
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Tech- Hematologic Emergencies (Part 3)
vti Mr.R Review
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