Pathology Images - Effect of Injury on Tissue 1

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Author:
ismansour
ID:
241937
Filename:
Pathology Images - Effect of Injury on Tissue 1
Updated:
2013-10-22 19:08:10
Tags:
Pathology Images Effect Injury Tissue Necrosis Coagulative Liquefactive Caseous Fibrinoid
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Description:
Path Images for Affect of Injury of Cells and Inflammation and Healing
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  1. Hydropic Change

    • Remember: Ischemia --> Hydropic Change
    • No O2--> no ATP --> Na + Water into cell
    • pH lowers, dilation of ER, ribosomes detach, cristae misalign. Blebbing
  2. Hydropic Change

    Remember: Ischemia --> Hydropic ChangeNo O2--> no ATP --> Na + Water into cellpH lowers, dilation of ER, ribosomes detach, cristae misalign. Blebbing
    • Areas of infarct
    • Note the "wedge" shapes
    • Necrosis Due to Infarct
    • Coagulative Necrosis
    • Caused by ischemia
    • Note the preservation of tissue architecture but the lack of nuclei

    Ex: myocardial infarction
    • Coagulative Necrosis
    • Caused by ischemia
    • Note the preservation of tissue architecture but the lack of nuclei
    • Ex:¬†myocardial infarction
    • Liquefactive Necrosis
    • Occurs in:
    • 1-brain injury due to ischemia (stroke)
    • 2- abcess formation

    You see no real structure or membranes usually. Just inflammatory cells
    • Liquefactive Necrosis
    • Occurs in:
    • 1-brain injury due to ischemia (stroke)
    • 2- abcess formation

    You see no real structure or membranes usually. Just inflammatory cells


    • Occurs in:
    • 1-brain injury due to ischemia (stroke)
    • 2- abcess formation
    • You see no real structure or membranes usually. Just inflammatory cells
    • Liquefactive Necrosis: Abcess
    • Difference from granuloma: note that abcess stains with eosin because of all the inflammatory cells
  3. Caseous Necrosis

    You can only use this term to describe grossly

    Microscopically: granuloma
  4. Fat Necrosis

    • 1) Enzymatic- most common cause is alcohol. inflammation causes leakage of digestive enzymes, which attack local fat cells. "ghost cells"
    • 2) Non-enzymatic- due to trauma
    • Fat Necrosis
    • 1) Enzymatic- most common cause is alcohol. inflammation causes leakage of digestive enzymes, which attack local fat cells. "ghost cells"
    • 2) Non-enzymatic- due to trauma
    • Fibrinoid Necrosis
    • microscopic change in arterioles, caused by malignant hypertension or autoimmune disease
  5. Apoptosis

    Intense Eosinophilia and loss of nucleus

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