Anticancer

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Author:
Neda317
ID:
242427
Filename:
Anticancer
Updated:
2015-01-20 15:04:02
Tags:
pharm
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Description:
pharm
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  1. L-asparginase
    G1
  2. mitomycin
    G1
  3. Cytarabine
    S-phase
  4. 6-Mercaptopurine (6MP)
    S
  5. 6-Thioguanine (6TG)
    s
  6. Methotrexate (MTX)
    s
  7. Hydroxyurea
    s
  8. Etoposide
    s
  9. Bleomycin
    G2
  10. Vinblastine
    M
  11. Vincristine
    M
  12. Paclitaxel
    M
  13. cyclophosphamide
    Alkylating Agents
  14. ifosfamide
    Alkylating Agents
  15. mechrorethamine
    Alkylating Agents
  16. melphalan
    Alkylating Agents
  17. chlorambucil
    Alkylating Agents
  18. busulphan
    Alkylating Agents
  19. Acrolein
    • Toxic to bladder, hematuria 
    • TX: MESNA
  20. Carmustine
    Nitrosurea
  21. lomustine
    Nitrosurea
  22. semustine
    Nitrosurea
  23. Cisplatin
    • Platinum
    • agents
  24. Cisplatin first generation 
    toxicity and TX
    • 1)Renal: Renal hydration and
    • Amifostine (cytoprotectant)

    • 2)peripheral sensory neuropathy, ototoxicity
    • (deafness)
  25. Carboplatin
    Platinum agents
  26. Oxaliplatin
    Platinum agents
  27. Carboplatin
    myelosuppression
  28. Oxaliplatin
    peripheralsensory neuropathy
  29. Procarbazine
    • non-phase specific 
    • Use: Hodgkin’s, NHL
  30. Dacarbazine (MM)
    non-phase specific
  31. Altretamine (OC)
    non-phase specific
  32. Busulphan
    •CML
  33. Busulphan
    A/E
    •skin pigmentation

    • •acute lung injury, chronic
    • interstitial fibrosis, alveolar hemorrhage (“busulphan lung”)

    • •Pulmonary
    • fibrosis

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