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What is the rate law for an Sn2 reaction?
rate = k[R-X][Nucleophile]
- so if you only double [R-X], then rate doubles. And if you only double [Nuc],
- then rate doubles as well.
What type of
nucleophile (weak or strong) favors an Sn2 reaction>
What is another
name for the sn2 reaction?
what is the Sn2 mechanism?
- Sn2 mechanism is a bimolecular (meaning that the transition state of the rate-limiting step involves two molecules) nucleophilic
- substitution. It is a concerted reaction (meaning that it takes place in a single step with bonds breaking and forming at the same time).
In order for a
carbon atom to be attacked by a nucleophile in an Sn2 reaction, what properties must the carbon atom to be attacked have?
- the carbon must be partially positive, it must
- have a good leaving group, the carbon must not be sterically hindered
must a chemical species meet in order to be a good leaving group?
- it must have electron withdrawing pwoer, it must be stable once it has left (i.e. it is not a strong base), and it must be
- polarizable to stabilize the transition state
The stronger a
nucleophile, the ____ the reaction in an Sn2 mechanism reaction
Strong bases are
strong _____, but not all ____ ____ are basic
- strong bases are strong nucleophiles, but not
- all strong nucleophiles are basic
Of a conjugate
acid-base pair, which is the stronger nucleophile?
the base is the stronger nucleophile
nucleophile strength _____ from left to right on the periodic table
decreases, because more electronegative atoms are less likely to form new bonds