Toxicology

Card Set Information

Author:
jstaylor
ID:
243040
Filename:
Toxicology
Updated:
2013-10-26 21:16:12
Tags:
medicine shelf
Folders:

Description:
medicine, toxicology and poisoning
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  1. Methanol poisoning
    • sx: headache, nausea, vomiting, epigastric pain; vision loss and coma
    • optic disc hyperemia
  2. Ethylene glycol poisoning
    • anion gap metabolic acidosis, increased osmolar gap
    • precipitates calcium oxalate crystals in the kidneys --> AKI
  3. Fluphenazine
    • Typical antipsychotic
    • injected every 2-3 weeks in schizophrenics
    • Can causeĀ hypothermia by inhibiting the body's shivering mechanism
  4. Neuroleptic malignant syndrome
    • presentation: confusion, fever, muscle rigidity, daphoresis, elevated CK
    • Tx: dantrolene (muscle relaxant), bromocriptine (dopamine agonist), amantadine (antiviral durg with dopaminergic properties)
  5. Torsades de pointes
    • risks: h/o alcoholism, recent initiation of fluconazole, moxifloxacin
    • Tx: stop all offending agents, administerĀ magnesium sulfate
  6. TCA overdose
    • hyperthermia
    • anticholinergic effects: dilated pupils, intestinal ileus
    • seizures
    • prolong GRS
    • Tx: sodium bicarbonate

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