What are the functions of Thyroxine (T4) & Triiodothyronine (T3)?
To regulate protein synthesis & enzyme activity & to stimulate mitochondrial oxidation.
What is the primary goal of the Thyroid gland?
^ bodies metabolism
necessary for G&D in children
What 3 hormones are secreted by the Thyroid gland?
Triiodothyronine (T3), Thyroxine (T4), Calcitonin
Explain how the Feedback mechanism works.
Regulates T4 & T3 secretion from the thyroid gland via the hypothalamus releasing Thyrotropin releasing hormone (TRH), which stimulates the release of TSH (Thyroid stimulating hormone), which stimulates the release of T3 & T4.
What is the etiology of Hypothyroidism?
Insufficient circulating thyroid hormone
What are the causes of Hypothyroidism?
Atrophy of gland w/aging
Irradiation, iodine deficiency or excess, Hashimoto's thyroiditis