Bacterial toxins page 1

Card Set Information

Author:
mame727
ID:
244266
Filename:
Bacterial toxins page 1
Updated:
2013-11-01 01:07:16
Tags:
page bacterial toxins
Folders:

Description:
Bacterial toxins
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user mame727 on FreezingBlue Flashcards. What would you like to do?


  1. Bacillus antracis
     (anthrax toxin, paeflf)
    Pa
    Ef
    Lf
    Disrupts cell signaling, cell migration, and cell death.

    • cell binding domain
    •       Facilitates the entry of either edema factor        or lethal factor.

    • Edema (swelling)
    •        Calmodulin-dependent adenylate cyclase
    •        ; increases cAmp in target cells. This                results in localized edema.

    • Pulmonary edema; anti-phagocytic
    •         Zinc-dependent protease that cleaves a           host signal transduction molecule.
  2. Bordetella pertussis (apt)
    Adelylate cyclase toxin
    Pertussis toxin
    Tracheal cytotoxin
    • Antiphagocytic, inhibits and kills leukocytes.
    •      Calmodulin-activated adenylate cyclase            causes an increase in target cell cAmp              levels and a decrease in atp production.            This modifies cell function, resulting in the          death of the cell.
    • Many hormonal effects
    •         Adp ribosylation of signal transducing G           protein blocks signal transduction.
    • Kills cilia-bearing cells.
  3. Campylobacter jejuni
    Enterotoxin
    • Diarrhea
    •      Adp ribosylation of signal transducing G proteins, blocks signal transduction.
  4. Clostridium botulinum
    Botulin (neurotoxin)
    • Flaccid paralysis
    •     Cleavage of neuromuscular presynaptic proteins blocks presynaptic junctions. This results in the decreased release of acetylcholine.
  5. Clostridium difficile
     Ec
    Enterotoxin
    Cytotoxin
    • Hemorrhagic diarrhea
    •     Acts at the membrane.

    Cells lose filaments
  6. Clostridium species
     alpha toxin
     beta toxin
     enterotoxin
    • Necrosis in gas gangrene; cytolytic; lethal
    •     Phospholipase c
    • Necrotic enteritis
    • Food poisoning; diarrhea
    •    Cytotoxin; damages membranes.
  7. Clostridium tetani
    tetanospasmin (neurotoxin)
    • spastic (rigid) paralysis
    •    cleavage of synaptobrevin prevents the release of gamma-aminobutyric acid and glycine from the synapses of inhibitory neurons.

What would you like to do?

Home > Flashcards > Print Preview