What is a platelet function test? What is meant by biphasic activation of platelets?
in vitro assay measuring platelet aggregation in response to various stimuli. Stimuli include: ADP, collagen, arachidonic acid, ristocetin, epinephrine. With some stimuli, response can be biphasic: low doses induce primary wave of activation and higher doses induce aggregation plus release of endogenous ADP, producing a secondary wave.