Describe the steps in thyroid hormone secretion from the hypothalamus, in addition to feedback mechanisms.
- 1. TRH released from hypothalamus.
- 2. TSH released from anterior pituitary.
- 3. TSH acts on follicular cells of thyroid gland to produce T3 and T4 which are secreted into blood and act on virtually all tissues in the body.
- 4. T3 levels sensed by both hypothalamus and ant.pituitary to provide negative feedback in order to regulate levels.