Blood Biochemistry 1
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What are the main roles of blood?
- Transports essential nutrients to tissues e.g. O2, glucose
- Removes waste products e.g. CO2
- Protects against infection
- Repair of tissue damage
What are the two types of oxygen carrying molecules in the body?
- Haemoglobin - abundant in red blood cells
- Myoglobin - oxygen store in muscle cells
What is the other term used for RBCs?
Name the process RBCs are made by and where it occurs?
- Bone marrow
What is the role of red blood cells?
To transport oxygen
What is the other term used for WBCs?
What are the three types of WBCs?
What are the two types of lymphocytes? Which produces antibodies?
- T and B lymphocytes.
- B lymphocytes produce antibodies
What are the different types of plasma proteins?
- Metal ion binding proteins
What are the main roles of albumin?
- Solubilisation, transport and removal of hydrophobic molecules in the hydrophilic environment of the plasma
- Maintaining osmotic balance between the plasma and tissue cells
What type of molecules does albumin transport?
- Fatty acids and sterols
- Some drugs e.g. penicillin
- Metal ions (non-specifically)
What are the metal ion transporters in the plasma and what do they transport?
- Albumin - involved in the non-specific transport of divalent and trivalent cations
- Transferrin - involved in the specific transport of Fe3+
- Ceruloplasmin - involved in the specific transport of Cu2+
What are metal ions essential for?
In the following which is present: plasma or serum?
- In vivo = plasma
- In vitro = serum
What is the difference between plasma and serum?
Serum has all the components of plasma except fibrinogen which is used up in the clotting process
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