Antiviral (9 questions)

Card Set Information

Author:
alvo2234
ID:
245745
Filename:
Antiviral (9 questions)
Updated:
2013-11-07 21:04:22
Tags:
Dr Mo
Folders:

Description:
PT III exam
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user alvo2234 on FreezingBlue Flashcards. What would you like to do?


  1. indinavir
    crixivan
  2. MOA of indinavir
    Protease inhibitor, prevents the breakdown of proteins on the virus
  3. tamiflu
    oseltamivir
  4. MOA of tamiflu
    neuroaminase inhibitor, prevents the virus from remaining undetected from host
  5. amantadine
    symmetrel
  6. MOA of amantidine
    • Inhibit the penetration and uncoating 
    • can increase the release of DA and inhibit the reuptake of DA
  7. AZT
    zidovudine; retrovir
  8. MOA zidovudine
    transformed to TriPO4 and inhibits rTranscriptase

    3' azido inhibits chain elongation
  9. raltegravir
    isentress
  10. MOA of raltegravir
    inhibits integration of the transcribed DNA to the host genome
  11. maraviroc
    selzentry
  12. MOA of selzentry
    blocks chemokine CCR-5
  13. Fuzeon
    Enfuvirtide
  14. AE of fuzeon
    • pneumonia
    • hypersensitivity 
    • injection site rxn (prominent)
  15. efavirenz
    sustiva
  16. AE of sustiva
    • skin- SJ,uticaria
    • CNS- paradoxical effects
    • increase cholesterol (10 -20% increase)
    • pancreatitis
    • dry mouth 
    • CVS- palpitation, tachycardia
  17. AE of AZT
    • BMD
    • CNS- insomia, wernickes encephalopathy
    • GI- enlarged tongue, dysgeusia
    • nail pigmentation
    • hepatotox
  18. S/sx of wernickes encephalopathy
    • stupor
    • hypothermia
    • nystagmus
  19. itraconazole
    sporonox
  20. MOA of itraconazole
    • PO; w/ food (oral suspension w/ or w/out)
    • metabolism; 3A4 (-OH has some activity)
    •                   also inhibits 3A4
    • t1/2; 30 - 40 hours
    • excretion; renal, breast milk
  21. what are the uses of ara-C
    • acute or chronic leukemia (ALL, AGL, CML)
    • burkitts lymphoma caused by EBV
    • chicken pox
    • shingles
  22. what are the uses of amantadine (symmetrel)
    • Flu A (no effect on Flu B)
    • rubella virus (german measles)
    • orthomoxyvirus/paramyxovirus
    • rubeola
  23. dosing for tamiflu
    75 mg PO BID x 5 days w/in 2 to 3 days of flu
  24. kg dosing for tamiflu
    • <15 kg        30
    • 15 - 23 kg    45
    • 24 - 40 kg    60
    • > 40 kg       80
  25. fluconazole dosing
    • vaginal candidiasis- 150 mg PO x 1
    • PID, UTI (candida)- 100-200mg QD
    • esophageal candidiasis; 50 - 100mg QD
    • cryptoc meningitis; 200-400 mg qd
    • coccidiodo mycosis; 600 mg QD
  26. drugs used to treat CMV
    • valcyclovir
    • adofovir
    • gancyclovir
    • formiveren
    • foscarnet
    • cidofovir
    • lubocovir
  27. drugs used to treat Hepatitis
    • adofovir 
    • emtricitabine
    • lamivudine
    • entecavir
    • cidofovir
    • tenofovir
    • interferons

What would you like to do?

Home > Flashcards > Print Preview