What do the following apoproteins do?
1. A1 (3)
2. B48, B100 (2)
3. CII, CIII (2)
4. E (1)
5. What is the reservoir of CII and E?
1. A1 - activates LCAT, receptor binding, found mostly on HDL (has been found on chylomicrons too)
2. B49, B100 - receptor binding (LDL-R) in peripheral tissues and liver, designates TAG delivery lipoproteins
3. CII, CIII - regulate LPL. CII activates LPL, CIII inhibits it.
4. E - receptor binding (hepatocytes recognize ApoE on chylomicron remnants and endocytose it).