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What are the 3 advantage of lipids as energy storage?
- 1. Highly reduced (38kj/g), more than twice of carbohydrate
- 2. Triacylglycerols (TAG) aggregate in droplets that doesn’t raise osmolarity of the cytosol
- 3. TAG are unsolvated and weight less than equal energy than in carb. In carb water takes 2/3 of weight.
Where can you find TAG?
Adipocytes or in dietary fat
Why is fat used as energy storage?
High E yield per gram, very hydrophobic therefore store in compact form
- - Major source of E in body
- - Excess dietary carb convert to TAG
What does Bile salt and pancreatic lipases do?
Breakdown dietary fat to fatty acids, glycerol, mono- and diglycerides for absorption by the intestine. Then the absorbed product used to resynthesize TAG in intestinal cell, then distributed to diff tissue by LIPOPROPROTIEIN.
How does TAG break down in circulation at peripheral tissues?
Hormone Sensitive Lipase (HSL)
- - Hydrolyze TAG to glycerols and free fatty acids on adipocyte
- - Provide mech to store fatty acid so can be distribute to other tissues
- - Hormone regulate glucogon/epinephrine and insulin
What transports fatty acids in blood?
What does fatty acid transporter do?
What is fatty acid oxidation?
Transport of fatty acid into the mitochondria
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