Card Set Information
sprozoites invade liver
Merozoites invade RBC'S
Gametocytes infect mosquito
Multi-phases seen, gametocytes appear early
could see baso stip.
troph compact -
may be seen
Gametocytes seen after weeks
Delicate ring forms & multiple per cell
Crescent shaped gametocyte
aftger 7-10 days
Oval shaped RBC's
Gametocytes seen 4-18 days after
typically mild ( mono like symptoms)
Can invade tissue in immunocomp.
: rising titers of ab's in serum
Babesia species life cycle
⇨ B. microti - US
⇨ B. divergens - Europe
Tick intorduces Sporoozytes
Trophozoites develop into merozoites
Gametocytes taken back by tick.
Maltese cross merozoites in RBC's
Causes Chagas disease (zoonitic disease)
US & Argentina & Poor rural areas of South America
trypanasomes cruzi Life Cycle
Insect bites human
Human scratches bite pushing in trapanosomes which penetrate various cells.
Trapanosomes transform into amastagote form.
Multiply in muscle and tissues
Burst out & Enters blood.
T. cruzi clinical disease
Acute phase typically asymptomatic
Chronic Stage may occur years or decades later
motile parasites (S or C shaped)
Amastagote in muscle
Trypanosoma: African sleeping sickness
⇨rhodesiense - East - wild game
⇨gambiense - West - human
Tsetse fly is host
parasite multiply in gut, transform into epimastigotes than into trypanomatigote
T. brucei disease
lesion at bite site
mono type symptoms, joint pain, CNS impairment
T. brucei Diagnosis
Examine fluid from bite site for trypomastigotes
* Late infection use CSF or lymph nodes
Leishmania spp. Life Cycle
Tropics and subtropics
Female Sand Flies - vector borne -
Promastigotes phagocytized by macrophages and transform into amastigotes.
Amastigotes affect tissue & blood
Caused by obligate intracellular protozoa
: 15-30 μm by 1.5- 4.0 μm
Kinetoplast located in the anterior end, where the flagellum leaves the cell
: inhabits the mammalian host
clear nucleaus and Central karyosome
No free flagellum
lesion with raised edges and central crater.
Cutaneous or visceral (kala-azar)
Fever, wt loss, swollen glans, spleen & liver.
low wbc,rbc,plt count
Micropsocpy form bone marrow, spleen, or lymph nodes