DNA Viruses

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ucstudent01
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247101
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DNA Viruses
Updated:
2013-11-15 18:23:42
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DNA Viruses
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DNA Viruses
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  1. All DNA Viruses discussed in this lecture are all dsDNA except which ONE?
    Parovirus
  2. Adenovirus

    Shape

    Diseases caused:
    • Icosahedral
    • Non enveloped

    Respiratory disease, eye inf., GI disease
  3. Hepadnavirus

    Shape

    Disease Caused
    dsDNA has short ss region

    • Icosahedral core
    • enveloped

    Hep B (surface & core Ag) (vaccine engineered)
  4. Herpesviruses

    Shape
    Diseases
    • Icosahedral nucleocapsid
    • enveloped

    HSV 1&2, VARICELLA, CMV,HHV 6-8,EBV,
  5. Varicella 

    Disease
    Stain/Identification
    Chicken pox & Shingles

    Tzanck stain of lesion - Giant Cells
  6. CMV

    Specimen
    Lab test
    Blood, urine, throat

    • shell vial cx
    • serology
  7. EBV

    Disease commonly associated with EBV
    Lab test
    Burkitts Lymphoma

    Serology: early Ag, Viral capsid Ag, Nuclear Ag
  8. HHV - 6,7, & 8

    Diseases found with each
    • 6:
    • ~Exanthema / Roseaola
    • **6th disease
    • Molecular test

    • 7:
    • Small percentage of reseaola

    • 8:
    • Kaposi's sarcoma
  9. Papillomavirus

    Diseases:
    • Warts
    • Cervical cancer
    • Laryngeal carcinoma

    Molecular assays
  10. Paroviruses

    Shape 
    Diseases
    Test
    Small non enveloped

    • *B19
    • 5ths disease
    • Aplastic crisis

    Molecular assay
  11. Poxviruses

    Size
    Shpae
    • replicated in cytoplasm
    • LARGEST virus

    • Complex:
    • Brick shape & Lipid envelope 

    Resistant to many environmental factors
  12. Disease associated with poxviruses
    Small pox - Variola

    Vaccinia: vaccine

    Moneypox: rare zoonitic Africa

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