dmrn1007

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Author:
blkbunny20
ID:
24799
Filename:
dmrn1007
Updated:
2010-06-27 15:08:34
Tags:
digestive drugs
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Description:
digestive system drugs
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  1. defense factors
    • mucus
    • bicarbonate
    • blood flow
    • prostaglandins
  2. aggressive factors
    • NSAIDs
    • smoking
    • H. Pyloris
    • pepsin
    • gastric acid
  3. prostaglandins
    suppress secretion of gastric acid
  4. helicobacter pylori (H. pylori)
    gram negative bacteria that colonize in stomach and duodenum
  5. zollinger-ellison syndrome
    tumor causes hypersecretion of gastric acid alone without bicarbonate
  6. 3 test to evaluate h.pylori eradication
    • serology
    • breath
    • biopsy
    • stool
  7. rantidine hydrochloride (Zantac)
    • H2RA
    • ADR
    • decrease libido
    • impotence
    • CNS effects
    • INTER
    • warfarin
    • phenytoin
    • antacids
  8. omeprazole (prilosec)
    • protein pump inhibitor (PPI)
    • ADR
    • none long term
    • long term cancer
    • INTER
    • ampicillin
    • digoxin
    • iron
    • ketoconazole
  9. sucralfate
    viscous substance that stick to ulcer for up to 6 hours
  10. sucralfate (carafate)
    • ADR
    • constipation
    • INTER
    • warfarin
    • phenytoin
    • digoxin
    • ciprofloxacin
    • antacids
  11. aluminum hydroxide gel (amphogel)
    • antacid
    • ADR
    • NA+ containing antacid
    • aluminum hydroxide
    • magnesium compounds
    • INTER
    • warfarin
    • tetracycline
  12. misoprostol (cytotec)
    • pregnancy risk X
    • ADR
    • dysmenorrhea
    • spotting
    • diarrhea
    • abdominal pain
  13. laxative
    • used to ease or stimulate defacation
    • produce soft stool over a day or more
  14. catharsis
    prompt fluid evacuation of the bowel
  15. bulk forming laxative
    psyllium (metamucil)
    • soften stool
    • increase bulk of stool
    • like dietary fiber
    • group III
  16. surfactant laxative
    ducosate (colace)
    • lower surface tension of stool to allow penetration of water
    • group III
  17. stimulant laxatives
    bisacodyl (dulcolax)
    • simulate intestinal peristalsis
    • increase water and electrolytes in intestinal lumen
    • PO or rectal
    • group II
  18. osmotic laxatives
    magnesium hydroxide
    (milk of magnesia)
    • draw water into intestines to incease bulk of stool
    • group I
  19. proctitis
    inflammation of lining of rectum
  20. Group I laxatives
    2-6 hr
  21. Group II laxative
    6-12 hrs
  22. group III laxatives
    1-3 days
  23. bisacodyl
    • rectal act in 15 min
    • group I
  24. esophageal obstruction
    • when you dont drink enough water with medicine
    • 8 oz
  25. intestinal obstruction
    if passage through intestines is arrested
  26. antiemetic receptor
    • 5ht3 serotonin
    • da2 dopamine 2
    • m muscarinic cholerginic
    • h1 histamin 1
    • nk1 neurokinin 1
  27. antiemetic
    given to supress nasea and vomiting
  28. ondansetron (zofran)
    • blocks 5ht3 receptor located in ctz and
    • on afferent vagal neurons in GI tract
    • po or iv
    • ADR
    • headache
    • dizziness
    • diarrhea
    • INTER
  29. prochloperazine (compazine)
    • blocks da2 receptors
    • ADR
    • hypotension
    • anticholinergic
    • eps
    • sedation
  30. dexamethasone (decadron)
    glucocorticoid
  31. dronabinol (marinol)
    • marijuana
    • ADR
    • dissociation
    • hypotension
    • dysphoria
    • tachycardia
  32. scopolamine (transderm scop)
    • muscarinic antagonist
    • ADR
    • anticholinergic effects
    • sedation
  33. dimenhydrinate (Dramimine)
    antihistamine
    • blocks h1 and muscarinic receptors
    • ADR
    • sedation
    • anticholinergic effects
  34. drug interaction for antiemetics
    • CNS depressants
    • antihypertensives
    • anticholinergic medications
  35. diarrhea
    • stools of excessive volume and fluidity
    • increased frequency of defacation
  36. diphenoxylate (lomotil)
    • opiod used for diarrhea
    • activiate opiod receptors in the GI tract to decrease intestinal motility
  37. metoclopramide (reglan)
    • prokinetic agents
    • ADR
    • eps
    • sedation
    • diarrhea
    • INTER
    • pt with seizures
  38. prokinetic agent
    block da2 and 5ht3 in CTZ
  39. h2ra suffix
    -dine
  40. proton pump inhibitors (ppi)
    suffix
    -azole

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