exam 4 drugs anesthetics and asthma

Card Set Information

Author:
iishvo
ID:
248013
Filename:
exam 4 drugs anesthetics and asthma
Updated:
2013-11-20 01:35:38
Tags:
pharm
Folders:

Description:
pharmacolgy drugs
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user iishvo on FreezingBlue Flashcards. What would you like to do?


  1. General anesthetics
    • nitric oxide-GABA agonist; NMDA antagonist
    • laudonum-powdered opiod, codine and morphine
  2. Volatile anesthetics
    • GABA agonist
    • very lipophilic¬†
    • liver toxicity
    • chloroform- increases depolarizations to increase K+ flux and causes cardiac arrhythmias
    • ether
    • isoflurone
    • halothane- trifluoracetic acid; 100,000x more acidic than acetic acid
  3. IV anesthetics
    • Benzodiazepines-Midazolam; GABA agnoist
    • Barbituates- Na+ thiopental; GABA agonist
    • Propafol- GABA agonist and Na+ channel blocker
    • Ketamine- NMDA glutamate antagonist
  4. Local anesthetics
    • Na+ channel blockers
    • decreases action potential/no depolarizations
    • esters-benzocaine and novacaine; metabolized by cholinesterases in blood/skin
    • amides-procainamide and lidocaine
  5. Brain surgery
    • propofal-GABA agonist; Na+ channel blocker
    • fentanyl-100x more potent than morphine
    • ultiva-opiod; 200x more potent than morphine
  6. Asthma
    • Bronchodilators-B2 receptors; Albuterol, Salmeterol, Terbutaline
    • Anti-cholinergic-M3 receptors; Atrovent
    • Tetraphyline- decreases phosphodiesterase which decreases cAMP to decrease release of chemical mediators
    • Anti-inflammatory agents:
    • Corticosteroids- decreases prostoglandins and histamines, increases interleukins; Predrisone and Flovent
    • Leukotriene inhibitors- Singulair, leukotriene receptor antagonist; zyflo, blocks leukotriene synthesis
  7. Bronchodilators
    B2 receptors; Albuterol, Salmeterol, Terbutaline
  8. Anti-cholinergic
    M3 receptors; AtroventTetraphyline- decreases phosphodiesterase which decreases cAMP to decrease release of chemical mediators
  9. Tetraphyline
    decreases phosphodiesterase which decreases cAMP to decrease release of chemical mediators
  10. Anti-inflammatory agents for Asthma
    Corticosteroids- decreases prostoglandins and histamines, increases interleukins; Predrisone 

    Leukotriene inhibitors- Singulair, leukotriene receptor antagonist; zyflo, blocks leukotriene synthesis

What would you like to do?

Home > Flashcards > Print Preview