Pregnancy drug

Card Set Information

Author:
Jjanggoo83
ID:
248966
Filename:
Pregnancy drug
Updated:
2013-11-25 12:31:29
Tags:
ADR Exam
Folders:

Description:
teratogenic
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Jjanggoo83 on FreezingBlue Flashcards. What would you like to do?


  1. ACE I (3 drugs in brands) 
    Cat. Effect?
    • Vostec (enalapril), Lotensin (benazepril),Zestril (lisinopril)
    • Stop immediately for pregnancy. affect all trimester.
  2. ARB 3 drugs
    • SAme as ACE-I; affect all trimester 
    • Cozaar (losartan) Diovan (Varsartan ), Benicar
  3. Lithium
    • for mania.. 
    • monitor fetal ECG ; cardiac anomalies = Ebstein's anomaly
  4. Anti-thyroid medications (hyperthyroidism)
    2 drugs; effect, category
    • TAPAZOLE (methimazole)
    • PTU (Propylthioluracil)
    • Category D, Cretinism(neonatal hypothyroidism)
  5. methotrexate
    Trexall, Cat.X, RA & Cancer
  6. misoprostol
    • Cytotec (brand)
    • ARthrotec  when w/ diclofenec.
    • Cate. X drug
  7. Bosentan and related drug
    tx for ? 
    cat?
    • Tracleer 
    • Ambrisentan
    • Cat.  X
    • pulmonary hypertension
    • REMS
  8. Mycophenolate
    use? category?
    • WAs C moved to D
    • Sifontis
    • use for transplant immunosuppressant
  9. What happen if take dilantin?
    • Phenytoin- Fetal hydantoin syndrome in 1st trimester (facial features)
    • neural tube defects
    • mental retardation
    • autististic features
    • ventral septal defect
    • hemorragic disease in 3rd trimester
  10. Carbamazepine & Phenytoin taking . what would you do?
    • Lower dose possible (Phenytoin- 10-20; Carbamazepine 4-12)
    • CAT.D
    • earlier- neural tube defect-> folic acid (take through out all pregnancy)
    • 3rd trimester- vit K metabolism induced(hemorrhage)-> vitamin K
    • Good nutrition- 
    • hypoalbuminemia-> increase concentration of drug taking ->more to placenta
    • tight monitoring
  11. what happen if take tegretol?
    • carbamazepine. cat. D
    • 1st trimester
    • neural tube defect, craniofacial defect, nail hypoplasia, developmental delay
    • 3rd trimester hemorrhagic disease
  12. Depakote
    generic name? category? 
    3 defects it can cause?
    when can it be used?
    only when used?
    Folic acid used?
    • CAt D: epilepsy/mania
    • Cat X: migraine / pain syndrome
    • - neural tube defect, Facial defect, retarded psychomotor development 
    • epilespy-> change if possible
    • mania: safer after neural tube closing (after 2nd trimester)
    • Folic acid Doesnt work!!
  13. Live vaccines
    • mumps 
    • measles
    • Rubella
    • Varicella
    • BCG
    • NAsal infulenza
  14. ARthrotec labeling
  15. - CI to women who are pregnant who may become pregnant 
    • - shouldnt be used childbearing potential age women unless hx of gastric, duodenal ulceration.
    • - (-) preganancy w/t 2 wks before tx
    • - able to comply w/ contraception 
    • - both oral , written counseling about potential risk of failure of contraception, damage to child
    • - will begin only on the 2nd or 3rd day of the next normal menstrual period
  16. Embryonic stage 
    3-8 wks; organogenesis
  17. most common effects of teratogens
    CNS
    3-16wks
  18. most comonefects of tertogens
    heart, limbs
    3-5 wks
  19. most comonefects of tertogens
    eye
    5-8
  20. most comonefects of tertogens
    ear, palate, teeth
    6-8
  21. most comonefects of tertogens
    external genitalia
    8-12 wks
  22. most comonefects of tertogens
    brain
    9-16wks
  23. what if take OC? 
    • feminize the fetus
    • even during 2nd trimester
  24. Dandy walker syndrome? 
    Warfarin earlier stage exposure
  25. hemorrhage? 
    • warfarin 3rd trimester
    • or antiepileptic 3rd trimester due to vit d deficiency. 
  26. Kernicterus
    • Bactrim 3rd trimester exposure 
    • due to hyperbilirubinemia
  27. bactrim
    • 1st- some teratogenic effect
    • 3rd- bound to albumin-> displace albumin making hyperbilirubinemia (jaundice)-> kernicterus (brain damage)
  28. hyperthyroid drug
    methimazole, PTU-> cretinism (hypothyroidsm)

What would you like to do?

Home > Flashcards > Print Preview