-May cause paradoxical slowing of HR if less than the therapeutic dose is given. (0.3mg adults, 0.1mg peds)
-Worsens glaucoma due to pupillary dilation
-Pupil reaction may not be a reliable indicator for hypoxic brain damage after atropine admin.
-Rule out hypoxia as cause of bradycardia in pediatric pts prior to admin.
-High doses of atropine may be reqd in organophosphate poisoning.