Card Set Information
Layers of the skin?
Epidermis is made of?
What are keranotinocytes?
Majority of the cells of the epidermis
Provides barries to skin
What are melanocytes?
at basal layer ( bottom line of the epideris layer)
make pigment melanin that get transferred to the keratinocytes in the basal cell layer
malignancy of melanocytes
suggests central cyanosis
arises in non-sun exposed areas
ass. w/ intermittent and intense sun exposure
blistering sunburns in childhood
- family hx of melanoma
- light skin
- presence of atypical moles (dysplastic nevi) or > 50 common moles
What are Langhern's cells?
3rd type of epidermal cells
dendritic cells at mid-epidermis
bind to antigen entering skin and transport them to lymph nodes
Characteristics of the dermis?
thicker than the epidermis
Made of fibroblasts and mast cells
- lymphatic vessels,
- nerves supplying the skin
- sweat glands
- hair follicles
What are fibroblasts?
resp. for synthesis and degradation of connective tissue protein
( dermal injury)
specialized cells resp for immediate type hypersensitivity reaction in skin
What is the subcutaneous layer?
fat layer that separates dermis from muscles
( inflammed nodules on sheen)
What are the characteristics of basal cell carcinoma?
ulcerated in the center nodules w/ shiny surfaces
erythematous papules and plaques
most common cancer
margin well defined
almost never spreads
What are the characteristics of squamous cell carcinoma?
affects outer layer of skin (
firmer and redder
hard scalling papules, nodules ot plaques that sometimes ulcerate and bleed
Atopic Dermatitis / Exzema
Genetic ( astham and rhinitis)
Chronic eruption of:
- pruritic erythematous, oozing papules and plaques
- w/ 2nd lichenification and excoriation
: extensor surface, diaper area, head
: flexor surface, upper chest, face, neck
Patient education about skin care to avoid cancer?
avoid unecessary sun exposure
use sunscreen, at SPF of 15 - water resistent if possible
inspect skin frequently
ACS recommendation about skin inspection?
q3 years --> clinician exam for people 20 - 39 yo
q1yr --> > 40
A - asymetry
B - border irregularity
C - color ( variation/ change)
D - diameter ( larger than 6 cm)
E - deviation
Refer suspicious lesions to dermatologist
Palor due to decreased redness
decreased blood flow