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  1. What are the 6 etiological agents for STDs?
    Neisseria gonorrhoeae, Chlamydiadiacaea, Treponema pallidium, Haemophilus durcreyi, Garnerella vaginalis, Calymmatobacterium granulomatis
  2. Why can't Treponema pallidium be cultured?
    it has spitocytes
  3. Haemophilus durcreyi can cause what?
  4. What is bacterial cystitis?
    • inflammation of the bladder
    • most common type
  5. Pyelonephritis (kidney infection) is a sequelae w/ what Sx's?
    abupt onset, burning pain, cloudy urine due to WBC, temp, chils, vomitting, pain
  6. What are the 6 etiological agents of cystitis?
    E. coli (70%), Klebsiella, Proteus, Staph saprophyticus, Serratia, Pseudo aeuruginosa
  7. Which ones are enterobactercocci?
    E. coli, Klebsiella, Proteus, Serratia
  8. What does Serratia produce?
    a rink pigment known as prodigiosin
  9. What is the pathogenesis of cystitis?
    ascended from the urethra
  10. Epidemiology of cystitis? occurs in who?
    • both sexes
    • paraplegia/catheterization
  11. In women what is it caused by?
    short urethra, sexual intercourse, use of diaphragm, wiping back to front
  12. In men what is it caused by?
    • age
    • benign prostatic hypertrophy
  13. Gonorrhea is what kind of bacteria? what host?
    • gm (-) diplococcus
    • humans ONLY natural reservoir
  14. What STD is the the 2nd most common?
  15. How many proteins are there in gonocovvus virulence factors?
    • Por protein (pI)
    • Opa protein (pII)
    • Rmp protein (pIII)
  16. What does the Opa protein do?
    mediates epithelium cell attachment
  17. What does the Rmp protein do?
    • Reduces modifiable
    • protects Por and LOS from attaching by antibodies
  18. What are the complications that occur with Gonorrhea?
    • Fitz-Hugh-Curtis syndrome
    • Disseminated infection to skin and joints
  19. Vaccine for gonnorrhea?
    • no
    • its immunogenic
  20. What Tx for Gonorrhea?
    Pen G IM, Deoxycycline, Cirpro, and Cefriazone
  21. What etiological agent causes chancroid?
    Haemphilus ducreyi
  22. Chancroid causes what? Seen where?
    • large ulcerative lesions--> can move to lymph nodes
    • tropics
  23. What does treponema pallidum cause?
  24. Treponema pallidum has what that is motile
    • motile spirochete
    • cant grow in vitro
  25. Pathogenesis of Treponema?
    • Entry: mucous memb, abraided skin, sex
    • Evasion: UNKNOWN  
    • Invasion: 1o, 2o, 3o,
  26. Primary syphilis
    • Chancre
    • due to inflam response
    • @ infection site
    • incubate 2-3 weeks
  27. Secondary syphilis
    • disseminated rash
    • lesions in mucous membranes
    • due to immune complexes binding treponemes
  28. How else can 2nd syphilis be transmitted?
    • through kissing
    • 50% resolves or goes to 3o
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