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How many species cause Shigellasis?
4 (S. dysenterine, S. flexerii, S. baydii, and S. serreri)
What kind of bacteria is this?
non-motile enteric bacteria
What does this bacteria invade?
lymphoid tissue in the lower intestine
What can certain strains produce?
What does the A subunit bind to? Causes?
binds to host cell ribosome
=inhibition of protein synthesis
What are the signs/symptoms of of dysentery?
What bacteria produces is different strain of dysentery?
diarrhea w/blood, pus, severe cramping
E. coli --> it is motile
What is gastroenteritis? caused by what?
inflammation of the stomach intestines
several types of E. coli
What are the 5 bacteria of E. coli?
What is ETEC known for? What 2 toxins does it produce?
traveler's diarrhea/infantile diarrhea
cholrea-like toxin & heat stable toxin=emetic
What is EPEC known for?
loss of microvilli
seen w/ nasoconical neonatal diarrhea
EHEC also know as what? Has a large what?
larger genome (pathogenetic islands)
What is EHEC (STEC) similar to?
toxin & of Shigella (verotoxin)
What disease can EHEC lead to?
hemalytic uremic syndrome (HUS)
The BIG 6 of E. coli are in what type of E. coli?
STEC or EHEC
What is a pathogenicity island?
huge chunk of DNA
about 10-100 kb
pathogenicity island contains genes for what?