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How many species cause Shigellasis?
4 (S. dysenterine, S. flexerii, S. baydii, and S. serreri)
What kind of bacteria is this?
non-motile enteric bacteria
What does this bacteria invade?
lymphoid tissue in the lower intestine
What can certain strains produce?
What does the A subunit bind to? Causes?
- binds to host cell ribosome
- =inhibition of protein synthesis
What are the signs/symptoms of of dysentery?
What bacteria produces is different strain of dysentery?
- diarrhea w/blood, pus, severe cramping
- E. coli --> it is motile
What is gastroenteritis? caused by what?
- inflammation of the stomach intestines
- several types of E. coli
What are the 5 bacteria of E. coli?
- Enterotoxigenic (ETEC)
- Enteroinvasive (EIEC)
- Enteropathogenic (EPEC)
- Enterohemorrhage (EHEC)
- Enteroaggregative (EAEC)
What is ETEC known for? What 2 toxins does it produce?
- traveler's diarrhea/infantile diarrhea
- cholrea-like toxin & heat stable toxin=emetic
What is EPEC known for?
- loss of microvilli
- seen w/ nasoconical neonatal diarrhea
EHEC also know as what? Has a large what?
- larger genome (pathogenetic islands)
What is EHEC (STEC) similar to?
toxin & of Shigella (verotoxin)
What disease can EHEC lead to?
- hemalytic uremic syndrome (HUS)
- kidney failure
The BIG 6 of E. coli are in what type of E. coli?
STEC or EHEC
What is a pathogenicity island?
- huge chunk of DNA
- about 10-100 kb
pathogenicity island contains genes for what?
- for virulence
- moves together