Ch 9 Notes

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  1. What is the acidity of terminal alkynes?
    alcohols?
    • pKa of 25
    • pKa of 16
  2. How do you form an acetylide?
    • expose it to a very strong base, which will strip the acetylide of its acetic proton
    • forms an acetylide salt
  3. Alkylation of Acetylide Ions
    Homologations using __rxn

    What must the electrophile be?
    • SN2 
    • primary
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Ch 9 Notes
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