Dermatophytes

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Author:
ucstudent01
ID:
251543
Filename:
Dermatophytes
Updated:
2013-12-10 19:11:26
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Dermatophytes
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Dermatophytes
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  1. Dermatophytes affect what?

    Location

    Most common
    • Hair, Skin, & Nails
    • World wide
    • Ringworm
  2. Name the 3 ways of transmision
    • 1. Geophilic = Soil to Man
    • 2. Zoophilic = Animal to Man
    • 3. Anthropophilic = Man to Man
  3. Types of infections of dermatophytes are?
    • Favic - Hair follicle, crusty lesion
    • Ectothrix - Colonized outside of shaft

    Endothrix - Hair follicle first, growth inside shaft

    Nail and nail bed - Onychomycosis

    Skin
  4. Lab Ident for dermatophytes
    • KOH (+calcofluor)
    • Woods Lamp - some fluoresce
    • Culture - SAB, 30C 4 weeks
    • Microscopic appearance
  5. Microsporum has 4 different species microscopic appearance for all are:
    • Macroconidia, thick walled, rough
    • Microconidia also usually present
  6. Microsporum audouinii lab info
    Anthropophilic (man to man)

    Woods lamp = Positive

    Rare distorted macroconidia, rare microconidia

    • Front: Light Tan
    • Back: Salmon to no color

    *No growth on sterile rice media
  7. Microsporum canis lab info
    Zoophilic

    Woods lamp = Positive

    • Front: Light tan, fluffy
    • Reverse: Bright yellow colony *especially on PDA

    • Large spindle shaped macroconidia (3-15 cells, tapering ends
    • Many Microconidia
  8. Microsporum gypseum lab info:
    • Geiophilic
    • Skin & hair

    Rapid Powdery/Granular buff to brown colony

    Rowboat shaped macrocondia (6 or less septa)
  9. Microsporum nanum
    Zoophilic

    Flat beige, brown or white 

    Small macroconidia (1 or 2 septa)

    *Rare cause of tinea corporis in humans
  10. Epidermophyton floccosum lab info
    • Anthropophilic
    • Tinea cruris, pedis, & unguium
    • *Does NOT infect hair

    Khaki - yellow colony

    *NO MICROCONIDIA

    Smooth walled, club shaped, groupings of macroconidia (beavers tail)
  11. 4 different Trichophyton spp.
    T. mentagrophytes

    T. rubrum

    T. tonsurans

    T. schoenleinii
  12. Trichophyton mentagrophytes lab info
    • Anthropophilic & zoophilic
    • Infects all 3 keratinized tissues
    • *Most common athletes foot (tinea pedis)

    • Front: Buff and powdery to white, cottony
    • Reverse: yellow, brown, colorless, or red

    • Spiral hyphae**
    • Round clustering microconidia and cigar shaped macroconidia

    • **UREASE = POSITIVE
    • **Hair perforation = Positive
  13. Trichophyton rubrum
    • Anthrophilic
    • *Ectothrix IF infect hair
    • **Most commonly infects skin & nails

    • Front: White & Fluffy
    • Reverse: Red

    • Tear drop shape microconidia
    • *May produce macroconidia

    • **UREASE = NEGATIVE
    • **Hair perforation = Negative
  14. Trichophyton tonsurans lab info
    • Anthrophophilic
    • *Endothrix
    • ⇨ Most common endothrix dermatophyte in US = Black dot *Tinea capititis


    Front: Beighe to olive granular with brwon rust edge

    Microconidia vary in shape and size

    **Requires thiamine
  15. Trichophyton schoenleinii
    • Anthropophilic
    • Endothrix

    SLOW - Orange/brown and wrinkled when young, flat when mature

    • NO Macroconidia, Rare Microconidia
    • *Antler shaped hyphae
  16. Treatment for all
    Kerotinolytic agen

    • Mild case - Topical azole
    • Scalp and more extensive - Griseofulvin
    • Nails - Griscofulvin or Itraconazole

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