Fungus-like bacteria

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Author:
ucstudent01
ID:
251771
Filename:
Fungus-like bacteria
Updated:
2013-12-09 09:20:39
Tags:
Bacteria that resemble fungus
Folders:
Fungus,like,bacteria
Description:
Fungus-like bacteria
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  1. Differentiation between Actinomyces, Nocardia, & Streptomyces
    • Actinomyces: Anaerobic - NOT acid fast - 
    • ALWAYS produce granules

    • Streptomyces: Aerobic -   NOT acid fast
    • May produce granules

    • Nocardia: Aerobic  -----  PARTIALLY acid fast
    • May produce granules
  2. Actinomyces spp. Lab info
    Most common * A. isralii

    • Endogenous,
    • GPR (or variable) Obligate anaerobe

    • Mouth & intestinal tract
    • Abscess at site of infection

    Diagnosis based off of direct microscopy
  3. Nocardia spp.

    Disease
    • Exogenous
    • Ubiquitous soil saprophytes
    • Route is inhalation or direct inocluation

    • N. asteroides is most common
    • N. brasiliensis is important in tropical areas

    Can colonize respiratory tract and then pneumonia then can disseminate (kidney, skin, GI tract, & brain are common targets)
  4. Nocardia lab info

    Micro
    Tap water
    hydrolyses
    Smell
    Macro
    • GVB beaded - Filamentous and branching
    • Modified acid fast - strict aerobic

    Tap Water - Recursively branching hyphae with aerial hyphae

    N. asteroidesDoes NOT hydrolyze

    N. brasiliensis - hydrolyzed casein & tyrosine


    • Colonies usually within 4 days
    • (could go up to 2-4 weeks) 

    Macro: Smooth, moist, or mold like: grey-white, waxy or powdery appearance

    *MUSTY/MILDEW ODOR
  5. Rhodococcus equi

    Disease & 

    Macro
    Micro
    Tapwater
    Hydrolysis
    Soil saprophyte associated with domestic *farm animals

    • Pulmonary infections that resemble TB
    •  ~ can spread to brain,liver,spleen. opportunistic

    • Macro:
    • 2-4 days - glistening smooth pink to red

    • Micro: 
    • GPCB

    *sometimes partially acid fast

    • Tap Water - NO branching helps to differentiate
    • Does NOT hydrolyze any

    Reverse CAMP positive
  6. Streptomyces spp

    Micro
    Macro
    Tapwater
    Hydrolysis
    • S. griseus - found in soil
    • NON - Pathogenic

    Musty smell

    • Macro:
    • 3-5 days at 35C
    • Waxy, white powdery top

    • Micro:
    • GP filamentous bacilli

    NON - acid fast

    Tap Water - Aerial tertiary branching

    • Hydrolyzes - all 3:
    • ~Casein, xanthine, & tyrosine
  7. Actinomanura spp.

    Disease
    Micro
    Tapwater
    Hydrolysis
    Common: A. madurae & pelletieri

    Causes: Mycetoma

    Only found in tropics

    Micro: GP filamentous bacilli

    Non acid fast

    Tapwater agar: Aerial, tertiary branching

    Hydrolyzes: Casein & Tyrosine
  8. Nocardiopsis spp.

    misc. info
    Soil saprophyte

    Thermotolerant *grows at higher temps

    Very rare case of mycetoma

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