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Cell responses mediated by phospholipase c activation
a peptide hormone that targets the liver and breaks down glycogen
targets pancreas to secrete amylase or targets smooth muscle for contraction
a proteolytic enzyme targets blood platelets and causes aggregation
phospholipase C activation
cleavage of inositol triphosphate from the phospholipid which leaves glycerol with two fatty acids attached
glycerol with two fatty acids attached
What pathway is important in memory function?
release of calcium which then binds to calmodulin induces a conformational change that enables it to bind to otherwise inactive kinases (CaM-kinases). phosphorylation of CaM-kinases sets off yet another signaling cascade.
single photoreceptor rod cell contains
multiple membrane discs of rhodopsin
a protein that captures light and transmits the signal through a g-protein called transducin
the alpha subunit of transducin
closes cation channels which changes the membrane potential . very fast signal on the order of 20 msec and you get a tremendous amplification of the signal. net change in membrane potential is about 1 mV