Chapter 16 Cell communication part 2
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Cell responses mediated by phospholipase c activation
- and thrombin
a peptide hormone that targets the liver and breaks down glycogen
targets pancreas to secrete amylase or targets smooth muscle for contraction
a proteolytic enzyme targets blood platelets and causes aggregation
phospholipase C activation
cleavage of inositol triphosphate from the phospholipid which leaves glycerol with two fatty acids attached
glycerol with two fatty acids attached
What pathway is important in memory function?
- Calmodulin action
- release of calcium which then binds to calmodulin induces a conformational change that enables it to bind to otherwise inactive kinases (CaM-kinases). phosphorylation of CaM-kinases sets off yet another signaling cascade.
single photoreceptor rod cell contains
multiple membrane discs of rhodopsin
a protein that captures light and transmits the signal through a g-protein called transducin
the alpha subunit of transducin
closes cation channels which changes the membrane potential . very fast signal on the order of 20 msec and you get a tremendous amplification of the signal. net change in membrane potential is about 1 mV
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