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What are the primary purpose for all NSAIDS?
How do all NSAIDS work in the body?
relieve pain, headache, fever and inflammation by blocking the release of prostoglandins
What is the purpose of analgesics and how do they work?
- treat headaches
- treat mild to moderate pain
- treat inflammation
- by blocking the chemical activity of prostaglandins
What is the purpose of antipyretic and how do they work?
- reduce fever
- by inhibiting prostaglandin E2 within the area of the brain that controls temperature
true/false. if a patient comes in the ED with major brain trauma, the nurse would expect for the patient temperature to be elevated.
true. the brain controls temperature
What are side effects of all NSAIDS?
- GI bleed
- mucosal lesions
- epigastric distress
- reduce creatinine clearance
- acute tubular necrosis with renal failure
What type of symptom(s) will a child or an adult be experiencing if they have an salicylate toxicity?
- child: hyperventilating and CNS effects
- adult: tinnitus and hearing loss
- metabolic acidosis and respiratory alkalosis also
What levels will indicate a potential for salicylate toxicity?
levels exceeding 40-60 mg/dL
What is the main purpose of allopurinol (Zyloprin)?
used to reduce production of uric acid
What is the main purpose of colchicine?
reduces inflammatory response to the deposits of urate crystals in joint tissue (reduce joint pain)
What is the main purpose of probenecid (Benemid) sulfinpyrazone (Anturane)?
increases excretion of uric acid in the urine
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