Effective doses.txt

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Author:
dohertys
ID:
25309
Filename:
Effective doses.txt
Updated:
2010-06-30 09:09:28
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Effective doses
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Description:
Effective doses of drugs
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  1. Most TCA's
    Dose range 50 to 75 mg --> 300 mg
  2. Amitriptyline
    50-300 mg TID
  3. Clomipramine
    • TCA
    • 25 - 250 mg OD
  4. Desipramine
    • TCA
    • 100 - 300 mg TID
  5. Doxepin
    • TCA
    • 75 - 300 mg TID
  6. Imipramine (Tofranil)
    • TCA
    • 75 - 300 mg TID
  7. Upper dose range of Amitriptyline, Desipramine, Doxepin, Imipramine.
    300 mg TID
  8. TCA with the lowest dose.
    • Protriptyline
    • 15-60 mg TID (long half life - 78 hrs)

    • Climipramine
    • 25 - 250 mg OD (long half life - 32 hrs)
    • (t0.5 of 7-26 hrs for other TCAs)
  9. TCA with largest dose?
    • Trimipramine (Surmontil)
    • range 150-600 mg TID
  10. Which 3 SSRI's have the same dose range? What is it?
    • Citalopram (Celexa)
    • Paroxetine (Paxil)
    • Fluoxetine (Prozac, Sarafem)

    20-60 mg OD (starting dose of 20 mg)
  11. SSRI with the longest half life? Shortest half life?
    • Fluoxetine (Prozac) - 72 hrs
    • Fluvoxamine (Lexapro) - 15 hrs

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