1. Why does Caesar mention his desire that Calpurnia stand “directly in Antonio’s way”?
... Calpurnia is barren, unable to have children. According to legend, a runner at the ancient Roman Lupercalia (a holy festival) could turn a barren woman fertile if he were to touch her during his run.
Caesar is urging Calpernia to stand "directly in Antonio's way" in the hopes that she may be made fertile by his touch. He then urges Antonio not to forget to reach out to her as he runs by.