Antineoplastics

Card Set Information

Author:
Mundi
ID:
253698
Filename:
Antineoplastics
Updated:
2013-12-18 02:18:16
Tags:
antineoplastic drugs
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Description:
Antineoplastics/Cancer cell specific drugs
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  1. Alkylating Agents
    Chlorambucil

    Take w/Mesna (↓ hemorr cystitis)

    No oral anticoagulants
  2. Antimetabolites
    Methotrexate

    • "Leukovorin rescue"
    • - 5-FU (potentiates
    • - MTX (child-sarcoma)

    Treats rheumatoid arthitis

    Photosensitivity (dark veins); ulcerative stomatitis
  3. Antineoplastic Antibiotic
    Doxorubicin

    AIDS related kaposi sarcoma, breast & testicular cancer

    Cardiac & pulmonary toxicity
  4. Protein Mitotic Inhibitor
    Vincristine

    Rhabdomyosarcoma

    D/D inject intrathecally

    Neurotoxic
  5. Hormone modulators
    Tamoxifen

    • Estrogen (block receptor site for hormone)
    • breast cancer

    Hot flashes, hypercalcemia, cario disease & accident
  6. Protein Tyrosine Kinase Inhibitor
    Imatinib

    • CML (leukemia)
    • GIST (gastro strom)
  7. Epidermal Growth Factors
    Erbtinib

    NSCLC  (non small cell lung cancer)

    Limited use toxic
  8. Proteasome Inhibitors
    Bortezomib

    Multiple Myeloma

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