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hypnotics treat what?
anxiolytics treat what?
hypnotics and anxiolytics are mostly from what groups?
- serotonine agonists
(diazepan, from the same group, treats SZ by potentiating GABA's inhib effect)
benzodiazapenes treat anxiety and sleep disorders how? (real basic)
enhance GABA mediated inhibition in the CNS
neuroleptics - treat what?
psychosis, schizo, esp auditory hallucinations, behavioral disturbances
neuroleptics - basic mechanism/type of drug
dopamine receptor antagonist
two mechanisms for anti-depressants
inhibit uptake of noradrenaline & serotonine
inhibit monomine oxidase
imipramine - type of drug? use?
a drug that inhibits uptake of serotonine and noradrenaline
imipramine - it's a tri-cyclic antidepressant
mineralocorticoides - type of corticosteroid released by adrenal cortex -- the main one? the main activity?
- salt retention
glucocorticoides - type of corticosteroid released by adrenal cortex -- the main one? the 2 main activities?
- affect carb and protein metabolism,
- suppress inflam, allergies, immune responses
3 glucocorticoids (an cortisol is a 4th? or the below are variations of cortisol?)
hydrocortisone, prednisolone, dexamethasone -- type of hormone? what metabolic effect?
stim gluconeogenesis, increase blood glucose --> insulin release
hydrocortisone, prednisolone, dexamethasone -- type of hormone? what anti-inflam effect?
inhibit formation of pro-inflam mediators (prostaglandins & leukotrienes)
hydrocortisone, prednisolone, dexamethasone -- type of hormone? what immunosuppresive effect?
- inhibit T & B lymphocyte function
- decrease macrophages and lymphoctes
oral anti-diabetic -- stronger than tolbutamide
oral anti-diabetic -- weaker than sulphonylure
insulin preparations - short, med, long
- short acting up to 7 h,
- medium acting up to 22h - semilente and lente mixture with zinc,
- long acting up to 36h - ultralente
- mixture with insoluble zinc crystals
thyroid gland secretes T3 &T4 -names?
responsible for what?
- T3 = triiodothyronine
- T4 = thyroxin
- optimal growth, development, function and maintenance of
- body tissues
calcitonin - produced where? regulates what?
- parafollicular cells
- calcium metabolism
synthesis of T3 (triiodothyronine) and T4 (thyroxin) requires what?
Grave's disease = hyperthyroidism -- treated with __ and __
thianomides - treats what? how?
- treats graves/hyperthyroidism
- block process of organification (iodine reacting w tyrosine to form...)
propranolol - treats what _ _ _
- high HR
2 drugs to treat hypothyroidism aka myxoedema
- thyroxine (T3)
- liothyronine (oral) (sodium salt of T4)