Drug treatment for Depression

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  1. Biological psychologists argue that depression is caused by a lack of which chemicals?
  2. Give three examples of monoamines
    • Adrenaline 
    • Dopamine 
    • Noradrenaline
  3. How do MOIs improve depressive symptoms?
    Monoamine Oxidase Inhibitors prevent the breakdown of neurotransmitters such as noradrenaline and serotonin meaning levels in the brain remain high
  4. What are the drawbacks of MAOIs?
    They are toxic and require dietary requirements
  5. What are the functions of Tricyclics?
    Slows the rate of re-absorption of noradrenaline and serotonin by preventing the re-uptake of neurotransmitters in the pre-synaptic vesicles of the brain
  6. When are MAOIs used?
    Only in cases where the patient does not respond well to other antidepressants
  7. State 3 side effects of MAOIs and Tricyclics
    • Possible heart attacks
    • Dizziness 
    • Erectile dysfunction
  8. How do SSRIs function?
    SSRIS function by preventing the re-uptake of serotonin in the presynaptic neuron, increasing serotonin levels in the brain
  9. Give an example of an SSRI
    Fluoxetine (Prozac)
  10. Give two factors that make SSRIs more viable than other drug treatment
    • SSRIs have fewer side effects
    • You cannot overdose on SSRIs
  11. How long does it take for SSRIs to yield symptomatic improvement?
    Usually within 2 weeks
  12. What is the foremost drug for Bipolar depression?
    Lithium carbonate
  13. What is lithium carbonate thought to do?
    Return dopamine and serotonin to normal levels
  14. What does the ineffectiveness of lithium carbonate in treating unipolar depression suggest?
    Unipolar and Bipolar depression have different causes
  15. Why must lithium carbonate be taken continuously?
    Discontinuation leads to mania
  16. State 3 side effects of lithium carbonate
    • Hand tremors 
    • Blurred vision
    • Kidney and liver dysfunction
  17. What did Gerbino et al find in 1978?
    Lithium carbonate reduces the occurrence of manic and depressive episodes in 80% of patients with bipolar depression
  18. What was the suicide rate of bipolar depression prior to the introduction of lithium carbonate?
    15% (it is now much lower)
  19. What are the rates of effectiveness for Tricyclics, MAOIs and SSRIs?
    • Tricyclics: 60%
    • MAOIs: 50%
    • SSRIs: 60%
  20. Describe Thase and Kupfers' 1996 study into the effectiveness of drug treatment
    • Review of studies comparing the effectiveness of antidepressants with placebos in blind trials
    • Acute depression was lifted in 50-70% of cases
    • This was 40% higher than in placebo groups
  21. What issues arise regarding the time taken for symptoms to improve?
    Drugs change the levels of neurotransmitters within hours yet symptoms take 3-5 weeks to improve suggesting there must be other factors at play
  22. What criticism did Cole raise in 1990?
    There have been reports that drugs such as Prozac are associated with suicidal urges
  23. Why is drug treatment criticised by freudian and cognitive psychotherapists?
    • Treatment does nothing to address the route cause of the depression, only treating the symptoms it produces 
    • Many patients attend psychotherapeutic sessions to deal with the external stressors
  24. How does treatment fallacy relate to drug treatment methods
    • Improvement in symptoms with treatment from chemicals does not prove that they are caused by a lack of said chemicals.
    • It is possible that depression causes the hormone imbalance
  25. What effects does drug therapy have on the lifestyle of a patient?
    Drug therapy allows people to integrate back into society, allowing them to keep symptoms under control and lead a normal life
  26. Why can drug treatment not be used for everyone?
    Some patients do not respond to antidepressants alone and must undergo other therapy types or multiple in conjunction
  27. What ethical issues arise regarding drug treatment?
    • Many drugs have upsetting and harmful side effects 
    • Misleading people into believing they are taking medication during studies involving placebos is morally questionable
Card Set:
Drug treatment for Depression
2014-01-02 10:46:25
Psychology Mood disorders Treatment camturnbull

AQA PSYB3 Psychology Mood disorders
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