Oncogenes

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  1. Gene: abl
    • Associated Tumor: CML
    • Gene Product: Tyrosine Kinase
  2. Gene: c-myc
    • Associated Tumor: Burkitt's lymphoma
    • Gene Product: Transcription factor
  3. Gene: bcl-2
    • Associated Tumor: Follicular and undifferentiated lymphomas (inhibits apoptosis)
    • Gene Product: Anti-apoptotic molecule
  4. Gene: HER2/ neu (c-erbB2)
    • Associated Tumor: Breast, ovarian, and gastric carcinomas
    • Gene Product: Tyrosine kinase
  5. Gene: ras
    • Associated Tumor: Colon carcinoma
    • Gene Product: GTPase
  6. Gene: L-myc
    • Associated Tumor: Lung Tumor
    • Gene Product: Transcription Factor
  7. Gene: N-myc
    • Associated Tumor: Neuroblastoma
    • Gene Product: Transcription Factor
  8. Gene: ret
    • Associated Tumor: Multiple endocrine neoplasia (MEN) types 2A and 2B
    • Gene Product: Tyrosine Kinase
  9. Gene: c-kit
    • Associated Tumor: Gastrointestinal stromal tumor (GIST)
    • Gene Product: Cytokine receptor
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255254
Card Set
Oncogenes
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