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Gene: Rb
- Associated Tumor: Retinoblastoma, osteosarcoma
- Gene Product: Inhibits E2F; blocks GI --> S phase
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Gene: p53
- Associated Tumor: Most human cancers, Li-Fraumeni syndrome
- Gene Product: Transcription factor for p21, blocks G1 --> S Phase
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Gene: BRCA1
- Associated Tumor: Breast and Ovarian Cancer
- Gene Product: DNA repair protein
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Gene: BRCA2
- Associated Tumor: Breast and Ovarian Cancer
- Gene Product: DNA repair protein
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Gene: p16
- Associated Tumor: Melanoma
- Gene Product: --
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Gene: BRAF
- Associated Tumor: Melanoma
- Gene Product: B-raf
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Gene: APC
- Associated Tumor: Colorectal cancer (associated w/ FAP)
- Gene Product: --
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Gene: WT1
- Associated Tumor: Wilms' Tumor (nephtoblastoma)
- Gene Product: --
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Gene: NF1
- Associated Tumor: NeuroFibromatosis type 1
- Gene Product: RAS GTPase activating protein (RAS-GAP)
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Gene: NF2
- Associated Tumor: NeuroFibromatosis type 2
- Gene Product: Merlin (schwannomin) protein
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Gene: DPC4
- Associated Tumor: Pancreatic Cancer
- Gene Product: DPC-Deleted in Pancreatic Cancer
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Gene: DCC
- Associated Tumor: Colon Cancer
- Gene Product: DCC-Deleted in Colon Cancer
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