ABSITE Basic Science/Transplant

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Author:
biochemjedi
ID:
256033
Filename:
ABSITE Basic Science/Transplant
Updated:
2014-01-14 16:22:32
Tags:
Basic Science Transplant
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questions on basic science
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  1. Cytokine most associated with cancer cachexia?
    TNF-Alpha
  2. Absolute contraindication to neuroaxial blockade?
    Coagulopathy
  3. mechanism of action of cyclosporine?
    IL-2 Blockade
  4. Main source of histamine in blood?
    basophils
  5. 3 electrolyte imbalances of refeeding syndrome?
    Decreased: PO, MG, K
  6. Tx of CMV in renal transplant patient?
    Ganciclovir
  7. Initial tx of coagulopathy associated with chronic renal failure?
    Desmopressin
  8. Relationship of R renal artery to IVC?
    Posterior
  9. Initial treatment of rejection following OLT transplant?
    Steriods
  10. Treatment of hepatitis B prior to OTL Tx?
    Lamuvidine
  11. Treatment of urokinase overdose?
    FFP
  12. Cytokin responsible for fever?
    IL-1
  13. Cell source of TNF alpha?
    macrophages
  14. Converts lymphcytes to lymphokine activated killer cells?
    IL-2
  15. Genetic abnormality in FAP?
    APC gene - chromosome 5
  16. Major cholesterol carrier in blood?
    LDL
  17. 3 factors of HCL release in stomach?
    • Gastrin
    • Histamine
    • ACH
  18. Intraaortic balloon pump inflation point?
    diastole/Twave
  19. 3 factors that cause right shift of O2/Hgb dissociation curve?
    • Increased CO2
    • Increased Temperature
    • Increased ATP
    • Decreased Ph
    • Increased 2,3 DPG
  20. Fuel for small bowel?
    glutamine
  21. Originating cell of glucagon release in pancreas
    Alpha cells
  22. Pulmonary function changes associated with aging?
    • Decreased FEV
    • Decreased vital capacity
    • Increased FRC
  23. Strongest bowel layer?
    submucosa
  24. predominant cell type in wound at day #1
    PMNs
  25. Time point of maximum tensile strength of wound?
    8 weeks
  26. Type of scar with excess collagen outside of incision?
    keloid
  27. Predominant collagen subtype in healed wound?
    type 3
  28. Treatment of Factor XI deficiency?
    FFP
  29. Initial tx of SIADH?
    Free water restriction
  30. CCK is produced in what two areas?
    Duodenum and the small bowel
  31. Cytokine that generates LAK cells?
    IL 2
  32. Primary food source of enterocytes?
    Glutamine
  33. Agent responsible for septic shock?
    Endotoxin
  34. Two anatomical structures that produce gastrin?
    Antrum and small bowel
  35. Enzyme that activates trypsinogen?
    Enterokinase

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